4D scanning transmission electron microscopy for structural biology

Project Information

4D-BioSTEM

Grant agreement ID: 101118656

DOI

10.3030/101118656

EC signature date 14 November 2023

Start date 1 January 2024

End date 31 December 2029

Funded under

• European Research Council (ERC)

Total cost

€ 7 489 397,00

EU contribution

€ 7 489 397,00

Coordinated by

FORSCHUNGSZENTRUM JULICH GMBH
Germany

CORDIS provides links to public deliverables and publications of HORIZON projects.

Links to deliverables and publications from FP7 projects, as well as links to some specific result types such as dataset and software, are dynamically retrieved from OpenAIRE .

Publications

Peer reviewed articles (10)

Cryogenic STEM of thick biological specimens

Author(s): Carsten Sachse
Published in: Nature Methods, 2025, ISSN 1548-7105
Publisher: Springer Nature
DOI: 10.1038/S41592-025-02818-9

Influence of loss function and electron dose on ptychography of 2D materials using the Wirtinger flow

Author(s): Leidl, Max Leo; Diederichs, Benedikt; Sachse, Carsten; Müller-Caspary, Knut
Published in: Micron, 2024, ISSN 1878-4291
Publisher: https://www.sciencedirect.com
DOI: 10.34734/FZJ-2024-04860

Benchmarking analytical electron ptychography methods for the low-dose imaging of beam-sensitive materials

Author(s): Robert, Hoelen L. Lalandec; Leidl, Max Leo; Müller-Caspary, Knut; Verbeeck, Jo
Published in: The European Physical Journal Applied Physics, 2025, ISSN 1286-0050
Publisher: https://www.edpsciences.org
DOI: 10.48550/ARXIV.2501.08874

Influence of the loss function on gradient-based iterative ptychographic reconstructions in 4D-STEM

Author(s): Leidl Max Leo; Sachse Carsten; Müller-Caspary Knut
Published in: BIO Web of Conferences, 2024, ISSN 2117-4458
Publisher: https://www.edpsciences.org
DOI: 10.1051/BIOCONF/202412904013

Pulsed-electron illumination does not reduce beam damage for imaging biological macromolecules

Author(s): Vishal Kumar; Julika Radecke; K.V. Chinmaya; Inayathulla Mohammed; Ricardo C. Guerrero-Ferreira; Daniel Harder; Dimitrios Fotiadis; Henning Stahlberg
Published in: Crossref, 2025, ISSN 2692-8205
Publisher: openRxiv
DOI: 10.1101/2025.07.29.667395

Towards a Protein-Size Dependent Resolution Limit due to Dynamical Scattering in Cryo-transmission Electron Microscopy

Author(s): Leidl, Max Leo; Sturm, Sebastian; Filopoulou, Aikaterina; Sachse, Carsten; Müller-Caspary, Knut
Published in: Microscopy and Microanalysis, 2025, ISSN 1435-8115
Publisher: Oxford University Press
DOI: 10.34734/FZJ-2026-00069

Nature Communications

Author(s): Berk Küçükoğlu; Inayathulla Mohammed; Ricardo C. Guerrero-Ferreira; Massimo Kube; Julika Radecke; Stephanie M. Ribet; Georgios Varnavides; Max Leo Leidl; Kelvin Lau; Sergey Nazarov; Alexander Myasnikov; Carsten Sachse; Knut Müller-Caspary; Colin Ophus; Henning Stahlberg
Published in: Nature Communications, 2024, ISSN 2041-1723
Publisher: Nature Publishing Group
DOI: 10.1038/S41467-024-52403-5

Aberration measurement by electron ptychography and consistency among different algorithms

Author(s): Tizian Lorenzen; Benedikt Diederichs; Charles Otieno Ogolla; Benjamin Butz; Knut Müller-Caspary
Published in: Applied Physics Letters, 2025, ISSN 1077-3118
Publisher: AIP Publishing
DOI: 10.1063/5.0238580

Following the Light: Enhancing Block Copolymer-Encapsulated Perovskite Nanocrystals Through In Situ Photoluminescence Measurements

Author(s): Patrick Ganswindt; Ekaterina Kostyurina; Leo Luber; Tizian Lorenzen; Andreas Singldinger; Jürgen Allgaier; Apostolos Vagais; Knut Müller-Caspary; Bert Nickel; Alexander S. Urban
Published in: Crossref, 2025, ISSN 2692-8205
Publisher: American Chemical Society
DOI: 10.26434/CHEMRXIV-2025-PBJCV

Cryo-electron microscopy in color

Author(s): Henning Stahlberg
Published in: Nature Methods, 2024, ISSN 1548-7105
Publisher: Springer Nature
DOI: 10.1038/S41592-024-02427-Y