Preventing Therapy Resistance in Esophageal Cancer Using Advanced Models and Molecular Signatures

Project Information

PRESSURE

Grant agreement ID: 101119464

DOI

10.3030/101119464

EC signature date 6 July 2023

Start date 1 February 2024

End date 31 January 2028

Funded under

Marie Skłodowska-Curie Actions (MSCA)

Total cost

No data

EU contribution

€ 2 717 755,20

Coordinated by

STICHTING AMSTERDAM UMC
Netherlands

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Deliverables

Plan for the dissemination and exploitation of results, including communication activities (1)

Plan for the dissemination and exploitation of results, including communication activities, submitted at mid-term (M13) and an update towards the end of the project (M48)

Omics data interrogation

Omics data package queried & candidate signaling molecules are targeted

EAC models

EAC model panel curated, propagation standardized, and shared between consortium members and interested researchers

Patient outreach

Communication to patients and relatives via ECPC press releases, newsletter, website and social media

Test stromal profiles

Pre-established stromal profiles are tested in materials from PRESSURE biobanks

Define contributions of EMT and purported CSCs

Define contributions of EMT and purported CSC populations to therapy resistance

Establish IP Board

IP board is established, Oncode supervises IP management