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A training network on the design of precision therapeutics that target key glycan motifs implicated in cancer

CORDIS provides links to public deliverables and publications of HORIZON projects.

Links to deliverables and publications from FP7 projects, as well as links to some specific result types such as dataset and software, are dynamically retrieved from OpenAIRE .

Publications

Structure, function, and implications of fucosyltransferases in health and disease (opens in new window)

Author(s): Mattia Ghirardello, Inmaculada Yruela, Pedro Merino, Robert Sackstein, Ignacio Sanz-Martínez, Ramón Hurtado-Guerrero
Published in: Nature Communications, Issue 16, 2025, ISSN 2041-1723
Publisher: Springer Science and Business Media LLC
DOI: 10.1038/S41467-025-66871-W

Chemical Strategies to Custom-Modify α(1→3)-Fucosylated Glycan Motifs of the Human Glycocalyx (opens in new window)

Author(s): Pedro Miguel Ascenso Vieira, Giacomo Biagiotti, Robert Sackstein, Barbara Richichi
Published in: JACS Au, Issue 5, 2025, ISSN 2691-3704
Publisher: American Chemical Society (ACS)
DOI: 10.1021/JACSAU.5C00716

A Rapid and Sensitive MicroPlate Assay (MPSA) Using an Alkyne‐Modified CMP‐Sialic Acid Donor to Evaluate Human Sialyltransferase Specificity (opens in new window)

Author(s): Kiamungongo Clairene Filipe; Sushmaa Dangudubiyyam; Cédric Lion; Mathieu Decloquement; Roxana Elin Teppa; Christophe Biot; Anne Harduin‐Lepers
Published in: ChemBioChem, 2024
Publisher: Chemistry Europe
DOI: 10.1002/CBIC.202400539

Advances in antibody-based strategies for targeting cancer-associated glycopeptide antigens (opens in new window)

Author(s): Edward P.W. Meier, Andreas H. Laustsen
Published in: Drug Discovery Today, Issue 30, 2025, ISSN 1359-6446
Publisher: Elsevier BV
DOI: 10.1016/J.DRUDIS.2025.104507

Realizing the promise of ‘La Dolce Vita’ via chemical biology: glycan‐motif editing of <scp>sLe<sup>X</sup></scp> for precision cancer therapeutics (opens in new window)

Author(s): Barbara Richichi, Robert Sackstein
Published in: The FEBS Journal, Issue 292, 2025, ISSN 1742-464X
Publisher: Wiley
DOI: 10.1111/FEBS.70079

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