Innovative Applications of Extracorporeal Photopheresis in Solid Organ Transplantation

Project Information

exTra

Grant agreement ID: 101119855

DOI

10.3030/101119855

EC signature date 13 July 2023

Start date 1 September 2023

End date 31 August 2027

Funded under

• Marie Skłodowska-Curie Actions (MSCA)

Total cost

No data

EU contribution

€ 2 613 103,20

Coordinated by

KLINIKUM DER UNIVERSITAET REGENSBURG
Germany

CORDIS provides links to public deliverables and publications of HORIZON projects.

Links to deliverables and publications from FP7 projects, as well as links to some specific result types such as dataset and software, are dynamically retrieved from OpenAIRE .

Publications

Peer reviewed articles (17)

Extracorporeal Photopheresis: From Animal Models to Clinical Practice

Author(s): Inês Morgado, Janaki Manoja Vinnakota, Robert Zeiser
Published in: Transplantation Direct, Issue 11, 2025, ISSN 2373-8731
Publisher: Ovid Technologies (Wolters Kluwer Health)
DOI: 10.1097/TXD.0000000000001824

Oncogene-induced TIM-3 ligand expression dictates susceptibility to anti–TIM-3 therapy in mice

Author(s): Nana Talvard-Balland, Lukas M. Braun, Karen O. Dixon, Melissa Zwick, Helena Engel, Alina Hartmann, Sandra Duquesne, Livius Penter, Geoffroy Andrieux, Lukas Rindlisbacher, Andrea Acerbis, Jule Ehmann, Christoph Köllerer, Michela Ansuinelli, Andres Rettig, Kevin Moschallski, Petya Apostolova, Tilman Brummer, Anna L. Illert, Markus A. Schramm, Yurong Cheng, Anna Köttgen, Justus Duyster, Hans D. Menssen, Jerome Ritz, Bruce R. Blazar, Melanie Boerries, Annette Schmitt-Gräff, Nurefsan Sariipek, Peter Van Galen, Joerg M. Buescher, Nina Cabezas-Wallscheid, Heike L. Pahl, Erika L. Pearce, Robert J. Soiffer, Catherine J. Wu, Luca Vago, Burkhard Becher, Natalie Köhler, Tobias Wertheimer, Vijay K. Kuchroo, Robert Zeiser
Published in: Journal of Clinical Investigation, Issue 134, 2024, ISSN 1558-8238
Publisher: American Society for Clinical Investigation
DOI: 10.1172/JCI177460

Comparison of four different assays to evaluate cellular-mediated immunity against cytomegalovirus in solid organ transplantation

Author(s): Angela Casas-Parra, Hendrik Veltman, Alba Romero-Caballero, Rosana Gelpi-Remiro, Marc Boigues-Pons, Imán Allalou, Ian Linares-Pardo, Anna Vila-Santandreu, Eva Martínez-Cáceres, María Iglesias-Escudero
Published in: Frontiers in Immunology, Issue 16, 2025, ISSN 1664-3224
Publisher: Frontiers Media SA
DOI: 10.3389/FIMMU.2025.1567253

Anti–PD-1 cancer immunotherapy induces central nervous system immune-related adverse events by microglia activation

Author(s): Janaki Manoja Vinnakota, Rachael C. Adams, Dimitrios Athanassopoulos, Dominik Schmidt, Francesca Biavasco, Alexander Zähringer, Daniel Erny, Marius Schwabenland, Marlene Langenbach, Valentin Wenger, Henrike Salié, James Cook, Omar Mossad, Geoffroy Andrieux, Rick Dersch, Sebastian Rauer, Sandra Duquesne, Gianni Monaco, Phillipp Wolf, Thomas Blank, Philipp Häne, Melanie Greter, Burkhard Becher, Philipp Henneke, Dietmar Pfeifer, Bruce R. Blazar, Justus Duyster, Melanie Boerries, Natalie Köhler, Chintan M. Chhatbar, Bertram Bengsch, Marco Prinz, Robert Zeiser
Published in: Science Translational Medicine, Issue 16, 2024, ISSN 1946-6234
Publisher: American Association for the Advancement of Science (AAAS)
DOI: 10.1126/SCITRANSLMED.ADJ9672

ECP-induced Apoptosis: How Noninflammatory Cell Death Counterbalances Ischemia/Reperfusion Injury

Author(s): Julia Stępień, Elke Eggenhofer
Published in: Transplantation Direct, Issue 11, 2025, ISSN 2373-8731
Publisher: Ovid Technologies (Wolters Kluwer Health)
DOI: 10.1097/TXD.0000000000001816

Targeting TGFβ-activated kinase-1 activation in microglia reduces CAR T immune effector cell-associated neurotoxicity syndrome

Author(s): Janaki Manoja Vinnakota, Francesca Biavasco, Marius Schwabenland, Chintan Chhatbar, Rachael C. Adams, Daniel Erny, Sandra Duquesne, Nadia El Khawanky, Dominik Schmidt, Viktor Fetsch, Alexander Zähringer, Henrike Salié, Dimitrios Athanassopoulos, Lukas M. Braun, Nora R. Javorniczky, Jenny N. H. G. Ho, Katrin Kierdorf, Reinhard Marks, Ralph Wäsch, Federico Simonetta, Geoffroy Andrieux, Dietmar Pfeifer, Gianni Monaco, Christian Capitini, Terry J. Fry, Thomas Blank, Bruce R. Blazar, Eva Wagner, Matthias Theobald, Clemens Sommer, Matthias Stelljes, Christian Reicherts, Astrid Jeibmann, Jens Schittenhelm, Camelia-Maria Monoranu, Andreas Rosenwald, Martin Kortüm, Leo Rasche, Hermann Einsele, Philipp T. Meyer, Joachim Brumberg, Simon Völkl, Andreas Mackensen, Roland Coras, Michael von Bergwelt-Baildon, Nathalie L. Albert, Laura M. Bartos, Matthias Brendel, Adrien Holzgreve, Matthias Mack, Melanie Boerries, Crystal L. Mackall, Justus Duyster, Philipp Henneke, Josef Priller, Natalie Köhler, Felix Strübing, Bertram Bengsch, Marco Ruella, Marion Subklewe, Louisa von Baumgarten, Saar Gill, Marco Prinz, Robert Zeiser
Published in: Nature Cancer, Issue 5, 2024, ISSN 2662-1347
Publisher: Springer Science and Business Media LLC
DOI: 10.1038/S43018-024-00764-7

Chimeric HLA antibody receptor T cell therapy for humoral transplant rejection

Author(s): Carolt Arana, Ainhoa Garcia-Busquets, Michael Nicoli, Sergi Betriu, Ilse Gille, Mirjam H M Heemskerk, Sebastiaan Heidt, Eduard Palou, Jordi Rovira, Fritz Diekmann
Published in: Nephrology Dialysis Transplantation, Issue 40, 2025, ISSN 0931-0509
Publisher: Oxford University Press (OUP)
DOI: 10.1093/NDT/GFAE160

Extracorporeal Photopheresis: Does It Have a Potential Place Among Cell-based Therapies?

Author(s): Panagiotis Parsonidis, Thomas Wekerle
Published in: Transplantation Direct, Issue 11, 2025, ISSN 2373-8731
Publisher: Ovid Technologies (Wolters Kluwer Health)
DOI: 10.1097/TXD.0000000000001808

Extracorporeal Photopheresis in Solid Organ Transplantation: Modulating B-cell Responses to Improve Graft Survival

Author(s): Filipe Nogueira, S. Marieke van Ham, Anja ten Brinke
Published in: Transplantation Direct, Issue 11, 2025, ISSN 2373-8731
Publisher: Ovid Technologies (Wolters Kluwer Health)
DOI: 10.1097/TXD.0000000000001833

Extracorporeal Photopheresis: Secreted Factors That Promote Immunomodulation

Author(s): Jorge H. Garcia-Almeida, Lukas Heger, Holger Hackstein
Published in: Transplantation Direct, Issue 11, 2025, ISSN 2373-8731
Publisher: Ovid Technologies (Wolters Kluwer Health)
DOI: 10.1097/TXD.0000000000001840

Exploring the Role of Extracorporeal Photopheresis in Kidney Transplant Management

Author(s): Michael Nicoli, Jordi Rovira, Fritz Diekmann
Published in: Transplantation Direct, Issue 11, 2025, ISSN 2373-8731
Publisher: Ovid Technologies (Wolters Kluwer Health)
DOI: 10.1097/TXD.0000000000001809

Oncogenic Calreticulin Induces Immune Escape by Stimulating TGFβ Expression and Regulatory T-cell Expansion in the Bone Marrow Microenvironment

Author(s): Dominik Schmidt, Cornelia Endres, Rouven Hoefflin, Geoffroy Andrieux, Melissa Zwick, Nikolaos Karantzelis, Hans F. Staehle, Janaki Manoja Vinnakota, Sandra Duquesne, Miriam Mozaffari Jovein, Dietmar Pfeifer, Heiko Becker, Bruce R. Blazar, Alexander Zähringer, Justus Duyster, Tilman Brummer, Melanie Boerries, Julian Baumeister, Khalid Shoumariyeh, Juan Li, Anthony R. Green, Florian H. Heidel, Itay Tirosh, Heike L. Pahl, Nils Leimkühler, Natalie Köhler, Marcelo A.S. de Toledo, Steffen Koschmieder, Robert Zeiser
Published in: Cancer Research, Issue 84, 2024, ISSN 0008-5472
Publisher: American Association for Cancer Research (AACR)
DOI: 10.1158/0008-5472.CAN-23-3553

Adiponectin reduces immune checkpoint inhibitor-induced inflammation without blocking anti-tumor immunity

Author(s): Lukas M. Braun, Sophie Giesler, Geoffroy Andrieux, Roxane Riemer, Nana Talvard-Balland, Sandra Duquesne, Tamina Rückert, Susanne Unger, Stefanie Kreutmair, Melissa Zwick, Marie Follo, Alina Hartmann, Natascha Osswald, Wolfgang Melchinger, Stefanie Chapman, James A. Hutchinson, Sebastian Haferkamp, Leopold Torster, Julian Kött, Christoffer Gebhardt, Dirk Hellwig, Nikolaos Karantzelis, Till Wallrabenstein, Theresa Lowinus, Mehtap Yücel, Niklas Brehm, Justyna Rawluk, Dietmar Pfeifer, Peter Bronsert, Manuel Rogg, Sven Mattern, Mathias Heikenwälder, Stefano Fusco, Nisar P. Malek, Stephan Singer, Annette Schmitt-Graeff, Fatih Ceteci, Florian R. Greten, Bruce R. Blazar, Melanie Boerries, Natalie Köhler, Justus Duyster, Gabriele Ihorst, Silke Lassmann, Philip Keye, Susana Minguet, Dirk Schadendorf, Selma Ugurel, David Rafei-Shamsabadi, Robert Thimme, Peter Hasselblatt, Bertram Bengsch, Christoph Schell, Erika L. Pearce, Frank Meiss, Burkhard Becher, Carolin Funke-Lorenz, Jan-Malte Placke, Petya Apostolova, Robert Zeiser
Published in: Cancer Cell, Issue 43, 2025, ISSN 1535-6108
Publisher: Elsevier BV
DOI: 10.1016/J.CCELL.2025.01.004

Extracorporeal Photopheresis Stimulates Tissue Repair after Transplantation

Author(s): Fabiola Arella, Hans J. Schlitt, Paloma Riquelme
Published in: Transplantation Direct, Issue 11, 2025, ISSN 2373-8731
Publisher: Ovid Technologies (Wolters Kluwer Health)
DOI: 10.1097/TXD.0000000000001812

Potential Impact of Extracorporeal Photopheresis on Trained Immunity and Organ Transplant Acceptance

Author(s): Clémentine Tocco, Jordi Ochando
Published in: Transplantation Direct, Issue 11, 2025, ISSN 2373-8731
Publisher: Ovid Technologies (Wolters Kluwer Health)
DOI: 10.1097/TXD.0000000000001835

Extracorporeal Photopheresis in Lung Transplantation: Present Applications and Emerging Research

Author(s): Sophia Alemanno, Peter Jaksch, Alberto Benazzo
Published in: Transplantation Direct, Issue 11, 2025, ISSN 2373-8731
Publisher: Ovid Technologies (Wolters Kluwer Health)
DOI: 10.1097/TXD.0000000000001831

Potential Biomarkers of Therapeutic Response to ECP in Solid Organ Transplantation

Author(s): Hendrik Veltman, Eva Martinez-Caceres, Maria Iglesias-Escudero
Published in: Transplantation Direct, Issue 11, 2025, ISSN 2373-8731
Publisher: Ovid Technologies (Wolters Kluwer Health)
DOI: 10.1097/TXD.0000000000001817