CROSS-SECTORAL ALLIANCE AS THE KEY FOR INNOVATION-DRIVEN BUSINESS SUCCESS OF ESTONIAN AND GREEK REPRODUCTIVE HEALTHCARE

Project Information

NESTOR

Grant agreement ID: 101120075

DOI

10.3030/101120075

EC signature date 12 June 2023

Start date 1 September 2023

End date 31 August 2026

Funded under

• Widening participation and spreading excellence

Total cost

€ 2 996 625,00

EU contribution

€ 2 996 625,00

Coordinated by

TARTU ULIKOOL
Estonia

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Links to deliverables and publications from FP7 projects, as well as links to some specific result types such as dataset and software, are dynamically retrieved from OpenAIRE .

Deliverables

Websites, patent fillings, videos etc. (1)

Website online and communication channels established

Develop projects visual identity, website and social media footprint.

Publications

Peer reviewed articles (14)

Generative artificial intelligence to produce high-fidelity blastocyst-stage embryo images

Author(s): Ping Cao; Josien Derhaag; Edith Coonen; Han Brunner; Ganesh Acharya; Andres Salumets; Masoud Zamani Esteki
Published in: Human Reproduction, 2024, ISSN 1460-2350
Publisher: Oxford University Press
DOI: 10.1093/humrep/deae064

Aging promotes accumulation of senescent and multiciliated cells in human endometrial epithelium

Author(s): M. Loid, D. Obukhova, K. Kask, A. Apostolov, A. Meltsov, D. Tserpelis, A. van den Wijngaard, S. Altmäe, G. Yahubyan, V. Baev, M. Saare, M. Peters, A. Minajeva, P. Adler, G. Acharya, K. Krjutškov, M. Nikolova, F. Vilella, C.Simon, M. Z. Esteki; A. Salumets
Published in: Human Reproduction Open, ISSN 2399-3529
Publisher: Oxford University Press
DOI: 10.1093/HROPEN/HOAE048

Prevalence of chromosomal alterations in first-trimester spontaneous pregnancy loss

Author(s): Essers, R., Lebedev, I.N., Kurg, A. et al.
Published in: Nature Medicine, 2023, ISSN 1078-8956
Publisher: Springer Nature Limited
DOI: 10.1038/s41591-023-02645-5

Endometrial Proliferative Phase-Centered View of Transcriptome Dynamics across the Menstrual Cycle

Author(s): Apostolov, A., Naydenov, M., Kalinina, A., Nikolova, M., Saare, M., Aleksejeva, E., Milova, N., Milov, A., Salumets, A., Baev, V., Yahubyan, G.
Published in: International Journal of Molecular Sciences, ISSN 1422-0067
Publisher: MDPI
DOI: 10.3390/IJMS25105320

Mitochondrial Venus is more likely to have a lower birthweight

Author(s): Elina Aleksejeva, Masoud Zamani Esteki, Andres Salumets
Published in: Trends in Endocrinology & Metabolism, 2024, ISSN 1879-3061
Publisher: Elsevier Ltd.
DOI: 10.1016/j.tem.2024.04.011

Carboxypeptidase inhibitor LXN expression in endometrial tissue is menstrual cycle Phase-Dependent and is upregulated in endometriotic lesions

Author(s): Sarsenova, M., Stepanjuk, A., Saare, M., Kasvandik, S., Soplepmann, P., Mikeltadze, I., Götte, M., Salumets, A., Peters, M.
Published in: Genes, ISSN 2073-4425
Publisher: MDPI
DOI: 10.3390/GENES15081086

ExplORRNet: An interactive web tool to explore stage-wise miRNA expression profiles and their interactions with mRNA and lncRNA in human breast and gynecological cancers

Author(s): Lawarde, A., Rahmani, E. S., Nath, A., Lavõgina, D., Jaal, J., Salumets, A., & Modhukur, V.
Published in: Non-coding RNA Research, 2023, ISSN 2468-0540
Publisher: Elsevier B.V.
DOI: 10.1016/J.NCRNA.2023.10.006

Clinical-grade whole genome sequencing-based haplarithmisis enables all forms of preimplantation genetic testing

Author(s): Anouk E. J. Janssen, Rebekka M. Koeck, Rick Essers, Ping Cao, Wanwisa van Dijk, Marion Drüsedau, Jeroen Meekels, Burcu Yaldiz, Maartje van de Vorst, Bart de Koning, Debby M. E. I. Hellebrekers, Servi J. C. Stevens, Su Ming Sun, Masoud Zamani Esteki
Published in: Nature Communications, ISSN 2041-1723
Publisher: Springer Nature Limited
DOI: 10.1038/S41467-024-51508-1

Reduced ovarian cholesterol and steroid biosynthesis along with increased inflammation are associated with high DEHP metabolite levels in human ovarian follicular fluids

Author(s): Varik, I., Zou, R., Bellavia, A., Rosenberg, K., Sjunnesson, Y., Hallberg, I., Holte, J., Lenters, V., Van Duursen, M., Pedersen, M., Svingen, T., Vermeulen, R., Salumets, A., Damdimopoulou, P., Velthut-Meikas, A.
Published in: Environment International, ISSN 1873-6750
Publisher: Elsevier Ltd.
DOI: 10.1016/J.ENVINT.2024.108960

Stanniocalcin protein expression in female reproductive organs: literature review and public cancer database analysis

Author(s): Khatun, M., Modhukur, V., Piltonen, T. T., Tapanainen, J. S., Salumets, A.
Published in: Endocrinology, ISSN 1945-7170
Publisher: Oxford University Press
DOI: 10.1210/ENDOCR/BQAE110

Endometriotic lesions exhibit distinct metabolic signature compared to paired eutopic endometrium at the single-cell level

Author(s): Sarsenova, M., Lawarde, A., Pathare, A. D. S., Saare, M., Modhukur, V., Soplepmann, P., Terasmaa, A., Käämbre, T., Gemzell-Danielsson, K., Lalitkumar, P. G. L., Salumets, A., Peters, M.
Published in: Communications Biology, ISSN 2399-3642
Publisher: Springer Nature Limited
DOI: 10.1038/S42003-024-06713-5

Exploring Immunome and microbiome interplay in reproductive health: current knowledge, challenges, and novel diagnostic tools

Author(s): Lingasamy, P., Modhukur, V., Mändar, R., Salumets, A.
Published in: Seminars in Reproductive Medicine, ISSN 1526-8004
Publisher: Thieme Medical Publishers, Inc.
DOI: 10.1055/S-0043-1778017

Epidemiologically relevant phthalates affect human endometrial cells in vitro through cell specific gene expression changes related to the cytoskeleton and mitochondria

Author(s): Visser, N., Silva, A. V., Tarvainen, I., Damdimopoulos, A., Davey, E., Roos, K., Björvang, R. D., Kallak, T. K., Lager, S., Lavogina, D., Laws, M., Piltonen, T., Salumets, A., Flaws, J. A., Öberg, M., Velthut-Meikas, A., Damdimopoulou, P., Olovsson, M.
Published in: Reproductive Toxicology, ISSN 0890-6238
Publisher: Elsevier Inc.
DOI: 10.1016/J.REPROTOX.2024.108660

Towards Metric-Driven Difference Detection between Receptive and Nonreceptive Endometrial Samples Using Automatic Histology Image Analysis

Author(s): Raudonis, V., Bartasiene, R., Minajeva, A., Saare, M., Drejeriene, E., Kozlovskaja-Gumbriene, A., Salumets, A.
Published in: Applied Sciences, ISSN 2076-3417
Publisher: MDPI
DOI: 10.3390/APP14135715