Organoid technologies for disease modeling, drug discovery and development for rare diseases

Project Information

ORGESTRA

Grant agreement ID: 101120108

DOI

10.3030/101120108

EC signature date 11 July 2023

Start date 1 January 2024

End date 31 December 2027

Funded under

Marie Skłodowska-Curie Actions (MSCA)

Total cost

No data

EU contribution

€ 3 455 308,80

Coordinated by

UNIVERSITEIT UTRECHT
Netherlands

CORDIS provides links to public deliverables and publications of HORIZON projects.

Links to deliverables and publications from FP7 projects, as well as links to some specific result types such as dataset and software, are dynamically retrieved from OpenAIRE .

Deliverables

Drug screening protocol

Protocols developed to expand and differentiate primary airway epithelium for drug development and individual drug efficacy testing in the context of multiple rare genetic airway diseases (DC6)

Training school 1 report

Completion and report on School 1

Training school 2 report

Completion and report School 2

Publications

When our treatment is complicated: an overview of drug-induced acid–base disorders: part 1—acidosis

Author(s): Giulia Florio, Detlef Bockenhauer
Published in: Pediatric Nephrology, Issue 41, 2026, ISSN 0931-041X
Publisher: Springer Science and Business Media LLC
DOI: 10.1007/S00467-025-06785-3

Drug Discovery Today

Author(s): Michiel Vanhaeren, Rik Gijsbers, Walter Van Dyck, Isabelle Huys, Steven Simoens
Published in: ISSN 1359-6446
Publisher: Elsevier
DOI: 10.1016/J.DRUDIS.2025.104459

A hydrophilic interaction liquid chromatography-tandem mass spectrometry method for the quantification of intracellular cystine and its application in cystinosis research

Author(s): Toon Verdonck, Roger Mora de la Serna, Patrick Augustijns, Rik Gijsbers, Deirdre Cabooter
Published in: Analytical and Bioanalytical Chemistry, 2026, ISSN 1618-2642
Publisher: Springer Science and Business Media LLC
DOI: 10.1007/S00216-026-06526-X

An Isogenic Human Myoblast Cell Model for Cystinosis Myopathy Reveals Alteration of Key Myogenic Regulatory Proteins

Author(s): Louise Medaer, Roger Mora, Zhuoheng Zhou, Nefele Giarratana, Laura Yedigaryan, Rita La Rovere, Elena Levtchenko, Vincent Mouly, Els Verhoeyen, Sebastiaan Eeltink, Achim Treumann, Tim Vervliet, Mauril
Published in: Journal of Cachexia, Sarcopenia and Muscle, Issue 16, 2025, ISSN 2190-5991
Publisher: Wiley
DOI: 10.1002/JCSM.70116

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Project Results

Deliverables

Publications

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