Non-canonical cleavage of GPR125/ADGRA3 releases extracellular receptor fragments detectable in cerebrospinal fluid
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Author(s):
Anna L.S. Walser, Olav Larsen, Chiara Stüdle, Nicoline Wichmand Thorsen, Florian Seufert, Anna Katarzyna Drzazga, Renata Mężyk-Kopeć, Isha Raj, Filippa Liliendahl Qvist, Sofie Morsing Bagger, Gertrud Malene Hjortø, Trine Toft-Bertelsen, Emily Slowikowski, Silvia Bergt, Eva Ganseman, Christoffer Knak Goth, Juliane Lokau, Christoph Garbers, Hiroshi Ishikawa, Horst Schroten, Paul Proost, Anja Hviid Simonsen, Nicholas M.I. Taylor, Joanna Bereta, Nanna MacAulay, Peter W. Hildebrand, Niels Henning Skotte, Katja Spiess, Tobias Langenhan, Michael J. Davies, Britta Engelhardt, Pedro E. Marques, Mette M. Rosenkilde
Published in:
iScience, Issue 29, 2026, ISSN 2589-0042
Publisher:
Elsevier BV
DOI:
10.1016/J.ISCI.2026.117551
Activation of cytomegalovirus-encoded G protein-coupled receptor UL33 by an innate N-terminal peptide
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Author(s):
Anna K. Drzazga, Shota Suzuki, Caroline Wouters, Felix Faas, Kouki Nishikawa, Akiko Kamegawa, Yoshinori Fujiyoshi, Mette M. Rosenkilde, Naotaka Tsutsumi
Published in:
Communications Biology, 2026, ISSN 2399-3642
Publisher:
Springer Science and Business Media LLC
DOI:
10.1038/S42003-026-09660-5
Neutrophils as critical orchestrators of chronic inflammation
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Author(s):
Kaat Torfs, Gaël Vermeersch, Mieke Gouwy, Timothy Devos, Paul Proost, Sofie Struyf
Published in:
Cellular & Molecular Immunology, 2026, ISSN 2042-0226
Publisher:
Springer Science and Business Media LLC
DOI:
10.1038/S41423-025-01380-W
Improving the in vivo activity of glycosaminoglycan-binding immunomodulatory drugs by fusion to human serum albumin
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Author(s):
Fabio Beretta, Lotte Agten, Vivian Louise Soares de Oliveira, Nele Berghmans, Christina Trojacher, Aid Atlic, Johannes Almer, Sofie Struyf, Roland Weis, Paul Proost, Andreas J. Kungl
Published in:
International Journal of Biological Macromolecules, Issue 339, 2026, ISSN 0141-8130
Publisher:
Elsevier BV
DOI:
10.1016/J.IJBIOMAC.2025.149825
Chemokines in the resolution of inflammation: key players and targets for therapeutic modulation
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Author(s):
Vivian Louise Soares Oliveira, Paul Proost, Sofie Struyf
Published in:
Frontiers in Immunology, Issue 16, 2025, ISSN 1664-3224
Publisher:
Frontiers Media SA
DOI:
10.3389/FIMMU.2025.1717666