Objective This research focuses on the increasing prevalence of metabolic liver disease, specifically non-alcoholic steatohepatitis (NASH), which is driven by obesity, diabetes, and its related causal connections. NASH is a significant medical challenge with no approved treatments, causing a substantial economic burden. The project aims to investigate the role of oxidative stress in NASH development and progression. By targeting the MAP kinases p38 and JNK, which drive the inflammatory and fibrotic aspects of NASH, our research could lead to new treatment approaches. Fields of science medical and health sciencesclinical medicineendocrinologydiabetesmedical and health sciencesclinical medicinehepatologymedical and health scienceshealth sciencesnutritionobesity Keywords NASHTARGET Programme(s) HORIZON.1.1 - European Research Council (ERC) Main Programme Topic(s) ERC-2023-POC - ERC PROOF OF CONCEPT GRANTS Call for proposal ERC-2023-POC See other projects for this call Funding Scheme HORIZON-ERC-POC - HORIZON ERC Proof of Concept Grants Coordinator KOBENHAVNS UNIVERSITET Net EU contribution € 150 000,00 Address Norregade 10 1165 Kobenhavn Denmark See on map Region Danmark Hovedstaden Byen København Activity type Higher or Secondary Education Establishments Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window EU contribution No data
