Engineering cancer dormancy as a collective emergent phenomenon: from matrix-enabled dormancy to collective dormancy-on-a-chip

Project Information

DORMATRIX

Grant agreement ID: 101123883

DOI

10.3030/101123883

EC signature date 21 June 2024

Start date 1 October 2024

End date 30 September 2029

Funded under

• European Research Council (ERC)

Total cost

€ 2 349 943,00

EU contribution

€ 2 349 943,00

Coordinated by

ASOCIACION INSTITUTO DE INVESTIGACION SANITARIA BIOGIPUZKOA
Spain

CORDIS provides links to public deliverables and publications of HORIZON projects.

Links to deliverables and publications from FP7 projects, as well as links to some specific result types such as dataset and software, are dynamically retrieved from OpenAIRE .

Publications

Peer reviewed articles (9)

Dynamic cancer dormancy and awakening emerge from tumor microenvironment feedback in a minimal theoretical model

Author(s): Guillermo Yáñez Feliú, Giacomo Rossato, Angelo Valleriani, Amaia Cipitria
Published in: npj Systems Biology and Applications, 2026, ISSN 2056-7189
Publisher: Springer Science and Business Media LLC
DOI: 10.1038/S41540-026-00827-8

Cancer Dormancy as a Collective Phenomenon Across Scales in Length and Time: Biological Observations and Advanced 3D Bioengineered Models

Author(s): Unai Heras, José Miguel Pardo-Sánchez, Laura Fallert, Dorleta Jiménez de Aberasturi, Oihane Mitxelena-Iribarren, Amaia Cipitria
Published in: Annual Review of Cancer Biology, Issue 10, 2026, ISSN 2472-3428
Publisher: Annual Reviews
DOI: 10.1146/ANNUREV-CANCERBIO-070824-124153

Dynamic cancer dormancy and awakening emerge from tumor microenvironment feedback in a minimal theoretical model

Author(s): Guillermo Yáñez Feliú, Giacomo Rossato, Angelo Valleriani, Amaia Cipitria
Published in: npj Systems Biology and Applications, 2026, ISSN 2056-7189
Publisher: Springer Science and Business Media LLC
DOI: 10.1038/S41540-026-00827-8

Stiffness and viscoelasticity of adipose tissue decellularized extracellular matrix hydrogels influence proliferation, growth pattern, migration and invasion of breast cancer cells

Author(s): Naike Salvador Moreno, Maria Mercedes Fernandez, Mikel Azkargorta, Iratxe Madarieta, Roberto Aguirresarobe, Felix Elortza, Beatriz Olalde, Amaia Cipitria
Published in: Biomaterials Advances, Issue 191, 2026, ISSN 2772-9508
Publisher: Elsevier BV
DOI: 10.1016/J.BIOADV.2026.215243

Nano-scale evidence for osteocyte network integration across bone remodeling interfaces in human bone revealed by synchrotron nanoCT

Author(s): Sophie Anuth, Emely Bortel, Julie Villanova, Jussi-Petteri Suuronen, Sven Geissler, Amaia Cipitria, Peter Fratzl, Tobias Fretwurst, Katja Nelson, Susanne Nahles, Bernhard Hesse
Published in: Materials Today Bio, Issue 37, 2026, ISSN 2590-0064
Publisher: Elsevier BV
DOI: 10.1016/J.MTBIO.2026.102813

Breast cancer cell-derived extracellular vesicles accelerate collagen fibrillogenesis and integrate into the matrix

Author(s): Nicky W. Tam, Rumiana Dimova, Amaia Cipitria
Published in: Materials Today Bio, Issue 38, 2026, ISSN 2590-0064
Publisher: Elsevier BV
DOI: 10.1016/J.MTBIO.2026.103133

Anisotropic hydrogel degradation enhances 3D collective mesenchymal stromal cell alignment, mechanotransduction and osteogenic differentiation

Author(s): Claudia A. Garrido, Daniela S. Garske, Christian H. Bucher, Shahrouz Amini, Georg N. Duda, Katharina Schmidt-Bleek, Amaia Cipitria
Published in: Acta Biomaterialia, Issue 204, 2026, ISSN 1742-7061
Publisher: Elsevier BV
DOI: 10.1016/J.ACTBIO.2025.07.063

Editorial special issue - Convergence of biomaterials science and cancer research

Author(s): Anna Taubenberger, Dietmar W. Hutmacher, Amaia Cipitria
Published in: Biomaterials Advances, Issue 177, 2025, ISSN 2772-9508
Publisher: Elsevier BV
DOI: 10.1016/J.BIOADV.2025.214396

Injectable and viscoelastic click alginate hydrogels for spatio-temporal T cell administration in vivo

Author(s): Jone Berasain, Sara Manzano, Oihane Mitxelena-Iribarren, Unai Heras, Ainhoa Romo-Valera, Peio Azcoaga, Leire Iturriaga, Leire Egia-Mendikute, Asís Palazón, Mercedes Fernández, María M. Caffarel, Robert Aguirresarobe, Amaia Cipitria
Published in: Materials Today Bio, Issue 38, 2026, ISSN 2590-0064
Publisher: Elsevier BV
DOI: 10.1016/J.MTBIO.2026.103128