Monocyte-to-Macrophage Trajectories After Lung Injury: Spatio-temporal investigation, molecular regulation & functional implications for lung regeneration and immunity

Project Information

MoMacTrajectALI

Grant agreement ID: 101124390

DOI

10.3030/101124390

EC signature date 20 June 2024

Start date 1 January 2025

End date 31 December 2029

Funded under

• European Research Council (ERC)

Total cost

€ 1 999 863,00

EU contribution

€ 1 999 863,00

Coordinated by

UNIVERSITE DE LIEGE
Belgium

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Links to deliverables and publications from FP7 projects, as well as links to some specific result types such as dataset and software, are dynamically retrieved from OpenAIRE .

Publications

Peer reviewed articles (4)

Endothelial-driven TGFβ signaling supports lung interstitial macrophage development from monocytes

Author(s): Wen Peng, Domien Vanneste, David Bejarano, Joan Abinet, Margot Meunier, Coraline Radermecker, Fabienne Perin, Didier Cataldo, Fabrice Bureau, Andreas Schlitzer, Qiang Bai, Thomas Marichal
Published in: Science Immunology, Issue 10, 2025, ISSN 2470-9468
Publisher: American Association for the Advancement of Science (AAAS)
DOI: 10.1126/SCIIMMUNOL.ADR4977

MafB is a conserved transcriptional regulator of macrophage development and functional identity across tissues and species

Author(s): Domien Vanneste, Wen Peng, Zhuangzhuang Liu, Malik Hamaïdia, Raphaël La Rocca, Joan Abinet, Alexis Balthazar, Fabienne Perin, Alexandre Hego, Didier Cataldo, Fabrice Bureau, Philippe Compère, Bénédicte Machiels, Charlotte L. Scott, Coraline Radermecker, Thomas Marichal
Published in: Immunity, Issue 59, 2026, ISSN 1074-7613
Publisher: Elsevier BV
DOI: 10.1016/J.IMMUNI.2026.01.012

Comparison of Droplet- and Microwell-based Methods to Analyze Cryopreserved Human BAL Cells by Single-Cell RNA Sequencing

Author(s): Pierre Janssen, Joan Abinet, Latifa Karim, Wouter Coppieters, Catherine Moermans, Julien Guiot, Florence Schleich, Coraline Radermecker, Thomas Marichal
Published in: American Journal of Respiratory Cell and Molecular Biology, Issue 73, 2026, ISSN 1044-1549
Publisher: Oxford University Press (OUP)
DOI: 10.1165/RCMB.2024-0467MA

Sensing of metabolic signals via GPR183 promotes occupation of lung macrophage niches by monocytes

Author(s): Laura Bub, Elza Evren, Stijn Verwaerde, Cecilia Ruscitti, Domien Vanneste, Pia Ghosh, Yu Gao, Natalie Sleiers, Rong Deng, Marta López Montes, Kelsey Howley, Raphaël La Rocca, Annika Niehrs, Vassilis Glaros, Maria Reina-Campos, Barbro Dahlen, Anna Smed-Sörensen, Harald Lund, Taras Kreslavsky, Niklas K. Björkström, Andrea Reboldi, Apostolos Bossios, Thomas Marichal, Bart N. Lambrecht, Tim Willinger
Published in: Journal of Experimental Medicine, Issue 223, 2026, ISSN 0022-1007
Publisher: Rockefeller University Press
DOI: 10.1084/JEM.20252667