Improving Kidney Health by Targeting Urinary Biomarkers for Tubular Function

Project Information

U-Tube

Grant agreement ID: 101125504

DOI

10.3030/101125504

EC signature date 24 January 2024

Start date 1 June 2024

End date 31 May 2029

Funded under

• European Research Council (ERC)

Total cost

€ 2 000 000,00

EU contribution

€ 2 000 000,00

Coordinated by

ERASMUS UNIVERSITAIR MEDISCH CENTRUM ROTTERDAM
Netherlands

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Links to deliverables and publications from FP7 projects, as well as links to some specific result types such as dataset and software, are dynamically retrieved from OpenAIRE .

Publications

Peer reviewed articles (8)

Roadblocks of Urinary EV Biomarkers: Moving Toward the Clinic

Author(s): Marvin Droste; Maija Puhka; Martin E. van Royen; Monica S. Y. Ng; Charles Blijdorp; Gloria Alvarez‐Llamas; Francesc E. Borràs; Anja K. Büscher; Benedetta Bussolati; James W. Dear; Juan M. Falcón‐Pérez; Bernd Giebel; Cristina Grange; Ewout J. Hoorn; Janne Leivo; Metka Lenassi; Alicia Llorente; Fabrice Lucien; Inge Mertens; Harald Mischak; Desmond Pink; Tobias Tertel; Swasti Tiwari; Dolores Di Vizio; Peter S. T. Yuen; Natasa Zarovni; Guido Jenster; Dylan Burger; Elena S. Martens‐Uzunova; Uta Erdbrügger
Published in: Journal of Extracellular Vesicles, 2025, ISSN 2001-3078
Publisher: Wiley
DOI: 10.1002/JEV2.70120

Toward Assessment of Tubular Function in Kidney Disease

Author(s): Sebastian B. Beckmann, Madonna Salib, Robert A. Fenton, Ewout J. Hoorn
Published in: Journal of the American Society of Nephrology, Issue 36, 2026, ISSN 1046-6673
Publisher: Ovid Technologies (Wolters Kluwer Health)
DOI: 10.1681/ASN.0000000705

American Journal of Physiology - Renal Physiology

Author(s): Eveline J. E. M. Kahlman; Martijn H. van Heugten; Lotte E. Tholen; Maartje F. A. Verploegen; Cornelia G. Spruijt; Pascal W. T. C. Jansen; Michiel Vermeulen; Joost G. J. Hoenderop; Ewout J. Hoorn; Tom Nijenhuis; Jeroen H. F. de Baaij
Published in: American Journal of Physiology-Renal Physiology, 2025, ISSN 1931-857X
Publisher: American Physiological Society
DOI: 10.1152/AJPRENAL.00167.2024

Urinary EGF Reflects Distal Tubular Mass and Is Associated with Hypertension, Serum Magnesium, and Kidney Outcomes

Author(s): Frank Geurts, Martijn H. van Heugten, Charles J. Blijdorp, Robert A. Fenton, Layal Chaker, Ewout J. Hoorn
Published in: Kidney360, Issue 6, 2025, ISSN 2641-7650
Publisher: Ovid Technologies (Wolters Kluwer Health)
DOI: 10.34067/KID.0000000687

Distinct proteomic signatures of urinary extracellular vesicles link to albuminuria and treatment responses in diabetic kidney disease

Author(s): Martijn H. van Heugten, Sebastian B. Beckmann, Madonna Salib, Viktor Rotbain Curovic, Jelle M. Beernink, Anna Faivre, Gozewijn D. Laverman, Qi Wu, Petter Bjornstad, Andrew M. Hall, Peter Rossing, Robert A. Fenton, Hiddo J.L. Heerspink, Ewout J. Hoorn
Published in: Kidney International, 2026, ISSN 0085-2538
Publisher: Elsevier BV
DOI: 10.1016/J.KINT.2026.04.018

Journal of the American Heart Association

Author(s): Frank Geurts; Layal Chaker; Anna C. van der Burgh; Deirdre Cronin‐Fenton; Robert A. Fenton; Ewout J. Hoorn
Published in: Journal of the American Heart Association, 2024, ISSN 2047-9980
Publisher: Wiley
DOI: 10.1161/JAHA.123.032835

Journal of the American Society of Nephrology : JASN

Author(s): Heugten, M.H. van; Blijdorp, C.J.; Arjune, S.; Willigenburg, H. van; Bezstarosti, K.; Demmers, J.A.A.; Musterd-Bhaggoe, U.; Meijer, E.; Gansevoort, R.T.; Zietse, R.; Hayat, S.; Kramann, R.; Müller, R.U.; Drenth, J.P.H.; Wetzels, J.F.M.; Salih, M.; Hoorn, E.J.
Published in: Journal of the American Society of Nephrology, 2023, ISSN 1046-6673
Publisher: American Society of Nephrology
DOI: 10.1681/ASN.0000000000000277

Association of Urinary PGE2 with Plasma Potassium in Patients with CKD and the General Population

Author(s): Frank Geurts, Martin Gritter, Dominique M. Bovée, Rosa D. Wouda, Liffert Vogt, Layal Chaker, Robert A. Fenton, Ewout J. Hoorn
Published in: Clinical Journal of the American Society of Nephrology, Issue 20, 2025, ISSN 1555-9041
Publisher: Ovid Technologies (Wolters Kluwer Health)
DOI: 10.2215/CJN.0000000653