Discovery of Covalent Ligands with AlphaFold3
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Author(s):
Yoav Shamir, Ronen Gabizon, Adi Rogel, David Yin-wei Lin, Amy H. Andreotti, Nir London
Published in:
Journal of the American Chemical Society, Issue 148, 2026, ISSN 0002-7863
Publisher:
American Chemical Society (ACS)
DOI:
10.1021/JACS.5C22222
Covalent Proximity Inducers
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Author(s):
Nir London
Published in:
Chemical Reviews, Issue 125, 2025, ISSN 0009-2665
Publisher:
American Chemical Society (ACS)
DOI:
10.1021/ACS.CHEMREV.4C00570
Covalent lysine targeting is coming of age
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Author(s):
Ella Livnah, Nir London
Published in:
Current Opinion in Chemical Biology, Issue 92, 2026, ISSN 1367-5931
Publisher:
Elsevier BV
DOI:
10.1016/J.CBPA.2026.102671
A pharmacological modality to sequester homomeric proteins
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Author(s):
Ella Livnah, Ohad Suss, Adi Rogel, Atar Gilat, Yuval Abdan, José A. Villegas, Ronen Gabizon, Almog Nadir, Yoav Shamir, Noam Y. Steinman, Barr Tivon, Shira Albeck, Tamar Unger, Ofra Golani, Inna Goliand, Nadav Elad, Silvia Carvalho, Khriesto Shurrush, Haim Barr, David Margulies, Emmanuel D. Levy, Nir London
Published in:
Nature Chemical Biology, Issue 22, 2026, ISSN 1552-4450
Publisher:
Springer Science and Business Media LLC
DOI:
10.1038/S41589-026-02141-0
α-Halothioamide warheads with enhanced cysteine reactivity and specificity for covalent protein labelling
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Author(s):
László Petri, Ronen Gabizon, Nikolett Péczka, Péter Ábrányi-Balogh, József Simon, Tímea Imre, György G. Ferenczy, Nir London, György M. Keserű
Published in:
Nature Communications, Issue 17, 2026, ISSN 2041-1723
Publisher:
Springer Science and Business Media LLC
DOI:
10.1038/S41467-026-72993-6
Thermodynamic characterisation of covalent ligand binding
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Author(s):
Rebecca Hertzman, Maayan Lavie, Almog Nadir, Ronen Gabizon, Nir London
Published in:
British Journal of Pharmacology, Issue 183, 2026, ISSN 0007-1188
Publisher:
Wiley
DOI:
10.1111/BPH.70574
