Morphogenesis meets Cell Fate: Dissecting how Mechanical Forces coordinate Development

Project Information

MechanoFate

Grant agreement ID: 101125803

DOI

10.3030/101125803

EC signature date 12 December 2023

Start date 1 March 2024

End date 28 February 2029

Funded under

• European Research Council (ERC)

Total cost

€ 2 000 000,00

EU contribution

€ 2 000 000,00

Coordinated by

FRIEDRICH-ALEXANDER-UNIVERSITAET ERLANGEN-NUERNBERG
Germany

CORDIS provides links to public deliverables and publications of HORIZON projects.

Links to deliverables and publications from FP7 projects, as well as links to some specific result types such as dataset and software, are dynamically retrieved from OpenAIRE .

Deliverables

Data Management Plan (1)

Data Management Plan

The Data Management Plan describes the data management life cycle for all data sets that will be collected, processed or generated by the action. It is a document describing what data will be collected, processed or generated and following what methodology and standards, whether and how this data will be shared and/or made open, and how it will be curated and preserved.

Publications

Peer reviewed articles (4)

Single-cell morphodynamics predict cell fate decisions during mucociliary epithelial differentiation

Author(s): Mari Tolonen, Ziwei Xu, Ozgur Beker, Varun Kapoor, Bianca Dumitrascu, Jakub Sedzinski
Published in: Molecular Systems Biology, Issue 22, 2026, ISSN 1744-4292
Publisher: Springer Science and Business Media LLC
DOI: 10.1038/S44320-026-00212-X

PAK4: A vanguard of epithelial vertex remodeling

Author(s): Raghavan Thiagarajan, Jakub Sedzinski
Published in: Journal of Cell Biology, Issue 225, 2026, ISSN 0021-9525
Publisher: Rockefeller University Press
DOI: 10.1083/JCB.202607020

ForSys: non-invasive stress inference from time-lapse microscopy

Author(s): Augusto Borges; Jerónimo R. Miranda-Rodríguez; Alberto Sebastián Ceccarelli; Guilherme Ventura; Jakub Sedzinski; Hernán López-Schier; Osvaldo Chara
Published in: iScience, 2024, ISSN 2589-0042
Publisher: Elselvier, Cell Press
DOI: 10.1016/J.ISCI.2025.113685

Protocol for inferring mechanical stresses in tissues using ForSys, an open-source Python tool

Author(s): Augusto Borges, Jerónimo R. Miranda-Rodríguez, Alberto S. Ceccarelli, Guilherme Ventura, Jakub Sedzinski, Hernán López-Schier, Osvaldo Chara
Published in: STAR Protocols, Issue 7, 2026, ISSN 2666-1667
Publisher: Elsevier BV
DOI: 10.1016/J.XPRO.2026.104595