Systemic approaches to improve cardiometabolic and brain health during lifespan

Project Information

SYS-LIFE

Grant agreement ID: 101126611

DOI

10.3030/101126611

EC signature date 17 October 2023

Start date 1 November 2023

End date 31 October 2028

Funded under

• Marie Skłodowska-Curie Actions (MSCA)

Total cost

No data

EU contribution

€ 3 152 160,00

Coordinated by

TURUN YLIOPISTO
Finland

CORDIS provides links to public deliverables and publications of HORIZON projects.

Links to deliverables and publications from FP7 projects, as well as links to some specific result types such as dataset and software, are dynamically retrieved from OpenAIRE .

Deliverables

Other (2)

Call 2: Link to Euraxess website

Inform the Project Officer on publishing each call for proposals, by sending the link to the Euraxess website and a screen shot of the related call announcement

Call 1: Link to Euraxess website

Inform the Project Officer on publishing each call for proposals, by sending the link to the Euraxess website and a screen shot of the related call announcement

Publications

Peer reviewed articles (23)

Harnessing nanoparticles for phytochemical delivery: a comprehensive review of safety and therapeutic potential

Author(s): Sharon Oladipupo, Damilare Emmanuel Rotimi, Emmanuel Henry Ezenabor, Adebola Busola Ojo, Oluwatomisin Aderonke Akinsola, Oluwafemi Adeleke Ojo
Published in: Therapeutic Delivery, 2025, ISSN 2041-5990
Publisher: Informa UK Limited
DOI: 10.1080/20415990.2025.2570638

The Impact of Maternal Supplementation of Fish Oil and/or Probiotics During Pregnancy on the Serum Metabolomic Profile From Infancy to Childhood: Secondary Analysis of a Randomized Placebo-Controlled Trial

Author(s): Veera Houttu, Dattatray Mongad, Noora Houttu, Lotta Saros, Chunpeng Zhang, Jenni Viitaharju, Tero Vahlberg, Leo Lahti, Kirsi Laitinen
Published in: Current Developments in Nutrition, Issue 9, 2025, ISSN 2475-2991
Publisher: Elsevier BV
DOI: 10.1016/J.CDNUT.2025.107553

The UPR-oxidative stress nexus in diabetes and obesity: Exploring innovative therapeutic approaches for metabolic control

Author(s): Clinton Ayodeji Akanbi, Oluwafemi Adeleke Ojo
Published in: Obesity Medicine, Issue 57, 2025, ISSN 2451-8476
Publisher: Elsevier BV
DOI: 10.1016/J.OBMED.2025.100634

Coronary atherosclerosis on AI-based plaque analysis in patients with chest pain and calcium score zero

Author(s): David Molnar, Juhani Knuuti, Jeroen J. Bax, Antti Saraste, Teemu Maaniitty
Published in: The International Journal of Cardiovascular Imaging, 2026, ISSN 1875-8312
Publisher: Springer Science and Business Media LLC
DOI: 10.5281/ZENODO.18316643

Advanced nanomaterials for myocardial ischemia-reperfusion injury: Bridging precision imaging to targeted therapy

Author(s): Jie Li, Muhammad Shafiq, Minghua Yao, Zehua Liu, Ruizhi Tian, Fangqiao Zheng, Chan Lu, Ming Ma
Published in: Smart Materials in Medicine, Issue 7, 2026, ISSN 2590-1834
Publisher: Elsevier BV
DOI: 10.5281/ZENODO.18340456

MSS-PAE: Saving Autoencoder-based Outlier Detection from Unexpected Reconstruction

Author(s): Xu Tan, Jiawei Yang, Junqi Chen, Sylwan Rahardja, Susanto Rahardja
Published in: Pattern Recognition, Issue 163, 2025, ISSN 0031-3203
Publisher: Elsevier BV
DOI: 10.1016/J.PATCOG.2025.11476

Parents’ Dental Anxiety in Early Pregnancy and Toothbrushing Stability for Parent and Child Until Age 4—A Longitudinal Study

Author(s): Arja Liinavuori, Risto Virtanen, Auli Suominen, Hanna Suokko, Vesa Pohjola, Mimmi Tolvanen, Mika Kajita, Hasse Karlsson, Linnea Karlsson, Satu Lahti
Published in: Dentistry Journal, Issue 14, 2026, ISSN 2304-6767
Publisher: MDPI AG
DOI: 10.5281/ZENODO.20588933

Tissue-Inducing Biomaterials for Cardiac Tissue Regeneration and Repair

Author(s): Muhammad Shafiq, Qasim A. Majid, Muhammad Rafique, Virpi Talman
Published in: Tissue Engineering Part A, 2026, ISSN 1937-3341
Publisher: SAGE Publications
DOI: 10.5281/ZENODO.18444518

MMM: A Unified Weakly-Supervised Anomaly Detection Framework for Multi-Distributional Data

Author(s): Xu Tan, Junqi Chen, Jiawei Yang, Jie Chen, Susanto Rahardja
Published in: IEEE Transactions on Knowledge and Data Engineering, Issue 38, 2025, ISSN 1041-4347
Publisher: Institute of Electrical and Electronics Engineers (IEEE)
DOI: 10.5281/ZENODO.20054744

Reliability and Validity of the Modified Dental Anxiety Scale Among Children Aged 9 to 12 Years

Author(s): Satu Lahti; Mika Kajita; Vesa Pohjola; Auli Suominen
Published in: Dentistry Journal, 2025
Publisher: ZENODO
DOI: 10.5281/ZENODO.18286676

Dental Anxiety as a Potential Bottleneck in Oral–Systemic Health Pathways: A Conceptual Mapping Review of Review Articles

Author(s): Mika Kajita, Vesa Pohjola, Gerald Humphris, Satu Lahti
Published in: Dentistry Journal, Issue 14, 2026, ISSN 2304-6767
Publisher: MDPI AG
DOI: 10.5281/ZENODO.19569311

Modest Longitudinal Associations Between Parent-Reported Dental Fear at Age 5 and Child-Reported Dental Fear at Age 9: A FinnBrain Birth Cohort Study

Author(s): Mika Kajita, Akie Yada, Vesa Pohjola, Linnea Karlsson, Hasse Karlsson, Satu Lahti
Published in: Dentistry Journal, Issue 14, 2026, ISSN 2304-6767
Publisher: MDPI AG
DOI: 10.5281/ZENODO.20553963

Level of Dental Anxiety and Its Role Among Barriers to Habitual Use of Oral Health Care in Adult Finns

Author(s): Vesa Pohjola, Anna Liisa Suominen, Mika Kajita, Pirjo Kurki, Ulla Harjunmaa, Satu Lahti
Published in: Dentistry Journal, Issue 14, 2026, ISSN 2304-6767
Publisher: MDPI AG
DOI: 10.5281/ZENODO.20588785

Life‐Course Blood Pressure Levels, 38‐Year Tracking, and Prediction of Hypertension

Author(s): Fiia Iiskala, Yaxing Meng, Markus Juonala, Costan G. Magnussen, Katja Pahkala, Nina Hutri, Mika Kähönen, Terho Lehtimäki, Mikael Fogelholm, Eero Jokinen, Tomi P. Laitinen, Leena Taittonen, Päivi Tossavainen, Antti Jula, Jorma Viikari, Olli Raitakari, Suvi Rovio
Published in: Journal of the American Heart Association, Issue 15, 2026, ISSN 2047-9980
Publisher: Ovid Technologies (Wolters Kluwer Health)
DOI: 10.5281/ZENODO.20044493

Gut Microbiome as a Risk Factor for Future CKD

Author(s): Tapio Hellman; Li-Fang Yeo; Joonatan Palmu; Aki Havulinna; Pekka Jousilahti; Ville Laitinen; Katariina Pärnänen; Veikko Salomaa; Leo Lahti; Rob Knight; Teemu Niiranen
Published in: Kidney International Reports, 2025
Publisher: ZENODO
DOI: 10.5281/ZENODO.18298445

Bioprospection of indigenous herbal formulations for diabetes care: in vitro, network pharmacology, and molecular dynamics studies

Author(s): Oluwafemi Adeleke Ojo; Akingbolabo Daniel Ogunlakin; Omolola Adenike Ajayi-Odoko; Gideon Ampoma Gyebi; Damilare IyinKristi Ayokunle; Adesoji Alani Olanrewaju; Oluwatobi Deborah Agbeye; Emmanuel Tope Ogunwale; Oluyomi Stephen Adeyemi
Published in: BMC Complementary Medicine and Therapies, 2025
Publisher: ZENODO
DOI: 10.5281/ZENODO.18279699

Test-Time Learning for Outlier Detection

Author(s): Jiawei Yang, Jingdong Chen, Susanto Rahardja
Published in: IEEE Transactions on Knowledge and Data Engineering, 2026, ISSN 1041-4347
Publisher: Institute of Electrical and Electronics Engineers (IEEE)
DOI: 10.5281/ZENODO.20054524

Exploring high dental anxiety subtypes using cluster analysis approach: a cross-sectional study

Author(s): Mika Kajita, Vesa Pohjola, Eeva-Leena Kataja, Satu Lahti
Published in: BMC Oral Health, Issue 25, 2025, ISSN 1472-6831
Publisher: Springer Science and Business Media LLC
DOI: 10.1186/S12903-025-06820-7

Associations between gut microbiome and circulating cytokines: a cross-sectional analysis in the FINRISK 2002 population cohort

Author(s): Diab, Hassan; Langen, Ville; Yeo, Li-Fang; Salomaa, Veikko; Havulinna, Aki; Lahti, Leo; Pärnänen, Katariina; Knight, Rob; Jalkanen, Sirpa; Salmi, Marko; Niiranen, Teemu; Palmu, Joonatan
Published in: Gut Pathogens, 2025
Publisher: ZENODO
DOI: 10.5281/ZENODO.18298228

Value of Multiomics Over Clinical Risk Factors in Hypertension Prediction

Author(s): Matti Vuori, Matti O. Ruuskanen, Pekka Jousilahti, Veikko Salomaa, Li-Fang Yeo, Anni Kauko, Felix Vaura, Aki Havulinna, Yang Liu, Guillaume Méric, Michael Inouye, Rob Knight, Leo Lahti, Teemu Niiranen
Published in: Hypertension, Issue 83, 2026, ISSN 0194-911X
Publisher: Ovid Technologies (Wolters Kluwer Health)
DOI: 10.5281/ZENODO.20048026

Ameliorative effect of Hibiscus sabdariffa leaf flavonoid extract on the PSA/CEA/AKT/MMP-9 signaling pathway in benign prostatic hyperplasia-induced rats

Author(s): Basiru Olaitan Ajiboye, Courage Dele Famusiwa, Efekemo Emmanuel Oghenemine, Agboola Deborah Imoleyemi, Olapade Samuel Akinlolu, Toluwase Hezekiah Fatoki, Abigail Omotayo Agbolade, Adetutu Omolola Ojelabi, Olawale Razaq Ajuwon, Babatunji Emmanuel Oyinloye, Marcello Iriti, Mary Abiola Okesola, Oluwafemi Adeleke Ojo
Published in: Comparative Clinical Pathology, Issue 34, 2025, ISSN 1618-565X
Publisher: Springer Science and Business Media LLC
DOI: 10.1007/S00580-025-03703-9

Exploring the Multifunctional Agents of Flavonoid‐Rich Beet Leaf Extracts: Insights From Experimental and Computational Studies

Author(s): Gideon Ampoma Gyebi, Damilare Emmanuel Rotimi, Moyosoreoluwa Oduba, Ifeoma Nnonyelu, Matthew Iyobhebhe, Musiliyu Ayofe Salawu, Adebola Busola Ojo, Odunayo Anthonia Taiwo, Adesoji Alani Olanrewaju, Abel Kolawole Oyebamiji, Mubarak Alruwaili, Naif H. Ali, Saud A. Alnaaim, Bshra A. Alsfouk, Gaber El‐Saber Batiha, Oluwafemi Adeleke Ojo
Published in: Food Safety and Health, Issue 3, 2025, ISSN 2835-1096
Publisher: Wiley
DOI: 10.1002/FSH3.70036

Sex differences in plaque burden and outcomes in symptomatic patients with suspected coronary artery disease

Author(s): David Molnar, Juhani Knuuti, Jeroen J. Bax, Antti Saraste, Teemu Maaniitty
Published in: International Journal of Cardiology, Issue 444, 2025, ISSN 0167-5273
Publisher: Elsevier BV
DOI: 10.1016/J.IJCARD.2025.134023