TUNGSTEN BIOCATALYSIS – HEAVY METAL ENZYMES FOR SUSTAINABLE INDUSTRIAL BIOCATALYSIS

Project Information

W-BioCat

Grant agreement ID: 101129798

DOI

10.3030/101129798

EC signature date 29 September 2023

Start date 1 February 2024

End date 31 January 2028

Funded under

• The European Innovation Council (EIC)

Total cost

€ 2 922 332,25

EU contribution

€ 2 922 332,25

Coordinated by

TECHNISCHE UNIVERSITEIT DELFT
Netherlands

CORDIS provides links to public deliverables and publications of HORIZON projects.

Links to deliverables and publications from FP7 projects, as well as links to some specific result types such as dataset and software, are dynamically retrieved from OpenAIRE .

Deliverables

Documents, reports (2)

Website and Logo

Website and project logo information with also social media links

Plan for Dissemination and Communication Activities

A detailed plan for the communication and dissemination of project findings to different target audiences is completed.

Data Management Plan (1)

Data Management Plan

Report on how data management will be approached

Publications

Peer reviewed articles (4)

Complete computational design of high-efficiency Kemp elimination enzymes

Author(s): Dina Listov; Eva Vos; Gyula Hoffka; Shlomo Yakir Hoch; Andrej Berg; Shelly Hamer-Rogotner; Orly Dym; Shina Caroline Lynn Kamerlin; Sarel J. Fleishman
Published in: Nature, 2025, ISSN 1476-4687
Publisher: Springer Nature
DOI: 10.1038/S41586-025-09136-2

Structural Insights Into CO ₂ Transport Pathways in a W‐Formate Dehydrogenase: Structural Basis for CO ₂ Reduction

Author(s): Guilherme Vilela‐Alves, Rita Rebelo Manuel, Guilherme Martins, Philippe Carpentier, Agata Raczyńska, Maciej Szaleniec, Inês A. Cardoso Pereira, Maria João Romão, Cristiano Mota
Published in: Angewandte Chemie International Edition, Issue 65, 2026, ISSN 1433-7851
Publisher: Wiley
DOI: 10.1002/ANIE.202526133

A database overview of metal-coordination distances in metalloproteins

Author(s): Bazayeva, Milana; Andreini, Claudia; Rosato, Antonio
Published in: Acta Crystallographica Section D Structural Biology, 2024, ISSN 2059-7983
Publisher: Structural Biology
DOI: 10.1107/s2059798324003152

Benchmarking Zinc-Binding Site Predictors: A Comparative Analysis of Structure-Based Approaches

Author(s): Cosimo Ciofalo, Vincenzo Laveglia, Claudia Andreini, Antonio Rosato
Published in: Journal of Chemical Information and Modeling, Issue 65, 2025, ISSN 1549-9596
Publisher: American Chemical Society (ACS)
DOI: 10.1021/ACS.JCIM.5C00549

Conference proceedings (1)

From BioEmu Monomer Ensembles to AMBER-Ready Holo Models: Subunit-Aware Quality Control of a Cofactor-Rich Aldehyde Oxidoreductase

Author(s): Piotr Dusza, Marek Wodziński, Maciej Szaleniec
Published in: Lecture Notes in Computer Science, Computational Science and Its Applications – ICCSA 2026 Workshops, 2026
Publisher: Springer Nature Switzerland
DOI: 10.1007/978-3-032-30536-7_13

Other (2)

A Computationally Designed Panel of Diverse and Selective Peroxygenases for Terpene Oxyfunctionalization

Author(s): Münch, J.; Soler, J.; Fleishman, S. J.; Garcia-Borràs, M.; Weissenborn, M. J.
Publisher: bioRxiv
DOI: 10.1101/2024.09.27.615329

High-Efficiency Kemp Eliminases by Complete Computational Design

Author(s): Listov, D.; Vos, E.; Hoffka, G.; Hoch, S. Y.; Berg, A.; Hamer-Rogotner, S.; Dym, O.; Kamerlin, S. C. L.; Fleishman, S. J.
Publisher: bioRxiv
DOI: 10.1101/2025.01.04.631280

Book chapters (1)

Tungsten containing aldehyde oxidoreductase (AOR)-family enzymes; past, present and future production strategies

Author(s): Deborah M. Boes, Rob A. Schmitz, Peter-Leon Hagedoorn
Publisher: Elsevier
DOI: 10.1016/BS.MIE.2025.01.027