Objective
The last two decades have witnessed giant experimental breakthroughs in different areas of the life sciences, from genomics to epidemiology. Thanks to modern high-throughput techniques, biological systems across multiple scales from single molecules up to entire populations can now be probed quantitatively at high spatial and temporal resolutions. Besides enhancing our basic knowledge of a systems constituents, these data potentially encode a plethora of information about the functional constraints that govern its evolution and the physical constraints that limit its performance, as well as about levels of organization, dynamical constraints or design principles that would be hard to identify from low-throughput data. Extracting this information is also crucial for applications ranging from the design of proteins with a desired functionality to the reconstruction of contacts during an epidemics. Inverse statistical mechanics attempts to do it by inferring generative models (Boltzmann distributions) from data using methods from the physics of disordered and random systems. Specific characteristics of biological data however, like strong undersampling and heterogeneity, limit the effectiveness of these tools. SIMBAD aims at developing a class of statistical inference techniques capable of overcoming these issues. In SIMBAD, theoretical work will supply concepts and methods to address four pressing problems (learning protein sequence landscapes, inverse modeling metabolic networks, inferring contact networks from epidemiological data, and improving survival analysis models), which in turn will guide the theory towards integration with the existing standards of each field. This effort promises to open new pathways for basic research to impact economic, technological and societal issues; the high- profile cross-disciplinary expertise represented in SIMBAD ensures instead for measurable and achievable objectives, placing SIMBAD in an ideal position to achieve its goals
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
- medical and health sciences health sciences public health epidemiology
- natural sciences biological sciences biochemistry biomolecules proteins
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Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
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HORIZON.1.2 - Marie Skłodowska-Curie Actions (MSCA)
MAIN PROGRAMME
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Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
HORIZON-TMA-MSCA-SE - HORIZON TMA MSCA Staff Exchanges
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Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
(opens in new window) HORIZON-MSCA-2022-SE-01
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Net EU financial contribution. The sum of money that the participant receives, deducted by the EU contribution to its linked third party. It considers the distribution of the EU financial contribution between direct beneficiaries of the project and other types of participants, like third-party participants.
10129 Torino
Italy
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.