Project description
Illuminating the future of faster diagnoses
In the realm of biomedical research, the limitations of current light sources hinder progress in crucial areas. Conventional instruments confine two-photon microscopy and time-resolved detection to specialised labs, impeding breakthroughs in cancer research and diagnostics. With this in mind, the EU-funded HILIGHT project aims to overcome existing limitations and pave the way for transformative advancements in biomedical and healthcare applications. Specifically, it will introduce a miniaturised optical pulse burst source and cutting-edge sensing technology. Two key applications underscore its potential impact: instantaneous digital histopathology and cancer research. With a consortium comprising leading partners from five European countries, the collaborative effort is expected to facilitate faster diagnoses and more effective treatments.
Objective
The overall objective of HILIGHT is to implement innovative solutions into versatile light sources and systems as tools for biomedical and healthcare applications centred around two-photon excitation fluorescence lifetime measurements and imaging microscopy. We propose two specific use cases: i) instantaneous digital histopathology and ii) biomedical research in the context of cancer research and diagnostics. HILIGHT proposes a miniaturised and versatile optical pulse burst source together with innovative sensing technology that will permit us to overcome those limitations in SoA instrumentation that often confine the use of two-photon microscopy and time-resolved detection to the specialist laboratory. We envisage that the HILIGHT innovations could disrupt activities in various fields and a range of market segments, including academic and research institutions, biotechnology, and medical facilities. These include applications targeted to improve our understanding of the molecular mechanisms of disease using in vivo, ex vivo, or 3D organotypic cultures, with the ultimate aim of developing better tools for fast and early diagnosis and more effective therapeutic interventions. HILIGHT is structured around nine work packages covering the whole value chain, coherently with the concept of the project standing on strong enabling technology foundations and targeting biophotonic and medical application domains. HILIGHT consortium is made up of five leading partners from various fields experienced in European collaborative projects and from five different European countries (FR, DE, IT, CH and UK). HILIGHT is built on several prior and ongoing successful collaborations between partners, which provides a strong guarantee for successful interaction within the consortium, and a smooth implementation of the workplan.
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HORIZON-RIA - HORIZON Research and Innovation ActionsCoordinator
91767 Palaiseau Cedex
France