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Multi-modal, configurable optical lab-on-chip platform for low-cost multipurpose diagnostics & monitoring

Project description

Multi-sensing platform for medical diagnostics and environmental threats monitoring

Miniaturised, multifunctional sensors are essential for accessing diverse chemical and biochemical information, which currently necessitates centralised laboratories and analytical techniques. Easy-to-use, rapid point-of-need sensors have the potential to revolutionise fields such as disease management, robotics and early detection of environmental threats. Nanophotonic devices offer promise in overcoming the limitations of current analytical methods, but are associated with significant challenges. The EU-funded MultiLab project aims to address these challenges by developing a flexible multi-sensing platform for medical diagnostics and IoT-based environmental monitoring. The platform utilises plasmonic augmented arrayed waveguide grating sensing, mid-IR photothermal spectroscopy and graphite-based electro-chemiluminescence sensing for multi-target detection. It will enable the detection of harmful algae blooms in freshwater sources and facilitate the diagnosis of fever without an apparent source.

Objective

There is an increasing need for miniaturised, multifunctional sensors providing simultaneous access to diverse chemical & biochemical information, required in various applications. Nowadays, such information, is routinely obtained by centralized laboratories and the use of analytical techniques. Although such methods will remain important when an immediate response is not necessary, easy-to-use, rapid point-of-need sensors that can be used by non-specialized personnel or even operate in a completely automated (unattended) manner could be a game-changer in a diverse range of fields such as disease management, robotics or for the early detection of environmental threats. Nanophotonic devices that precisely control light in subwavelength volumes and enhance light–matter interactions, have opened up new prospects for sensing applications, addressing the limitations of current analytical methods in terms of sensitivity, ease-of-use and miniaturization. There are, though, challenges to be overcome.
MultiLab addresses these challenges by developing a highly flexible multi-sensing platform compatible with wafer scale manufacturing that will integrate multiple sensing modalities to simultaneously detect biological, chemical, microorganism and molecular targets for medical diagnostics & IoT-based environmental monitoring. The sensing modalities integrated in the MultiLab platform are a) plasmonic augmented, Arrayed Waveguide Grating sensing on a Si3N4 photonic platform for true & scalable multiplexed detection, b) mid-IR PTS employing the same SiN photonic platform for on-chip interferometric sensing by means of MZIs including also the same plasmonic devices and optical read-out as for the PA-AWG, c) graphite-based electro-chemiluminescence sensing. The system will be demonstrated in two applications: a) IoT-enabled, early warning of harmful algae blooms in fresh water sources, b) diagnosis & prognosis of fever without an apparent source.

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Keywords

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Programme(s)

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Topic(s)

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Funding Scheme

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HORIZON-RIA - HORIZON Research and Innovation Actions

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Call for proposal

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(opens in new window) HORIZON-CL4-2023-DIGITAL-EMERGING-01

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Coordinator

CY.R.I.C CYPRUS RESEARCH AND INNOVATION CENTER LTD
Net EU contribution

Net EU financial contribution. The sum of money that the participant receives, deducted by the EU contribution to its linked third party. It considers the distribution of the EU financial contribution between direct beneficiaries of the project and other types of participants, like third-party participants.

€ 626 250,00
Address
AGIAS ELENIS 6 AGIAS ELENIS BUILDING 4TH FLOOR FLAT OFFICE 43
1060 Lefkosia
Cyprus

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SME

The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed.

Yes
Region
Κύπρος Κύπρος Κύπρος
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
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Total cost

The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.

€ 626 250,00

Participants (11)

Partners (1)

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