Project description
Molecular analysis with quantum sensing
Understanding the structure of molecules is essential in many fields, from developing new medicines to creating advanced materials. Nuclear magnetic resonance (NMR) spectroscopy is one of the most powerful tools for this, but traditional NMR machines are still limited by their sensitivity. They rely on technology that has remained largely unchanged for 80 years, using strong magnets and induction coils. A new approach using tiny quantum sensors in diamonds has shown promise, but for real world applications it still needs improvement. The EU-funded QUENCH project aims to improve the sensitivity of NMR through the combination of this quantum sensing technology with advanced diamond materials. By increasing sensitivity, the project will open up new possibilities for molecular analysis in medicine, industry, and environmental science.
Objective
Nuclear magnetic resonance (NMR) spectroscopy is the workhorse of modern molecular structural analysis with countless scientific applications, from materials science to drug discovery. Nevertheless, even the most modern NMR spectrometers still employ the same principles as 80 years ago, induction coils and high magnetic fields, making them bulky, expensive, and inaccessible to many potential users. However, a novel type of NMR sensor emerged recently from solid-state spin quantum systems: the nitrogen-vacancy (NV) center in diamond, which has demonstrated unparalleled sensitivities in detecting NMR signals. In this proposal, we aim to significantly enhance the sensitivity of modern benchtop NMR spectrometers by several orders of magnitude. We will achieve this improvement by combining the NMR technology field with cutting-edge quantum sensing, employing improved NV-diamond materials, advanced microwave antennas, novel pulse sequences, and quantum control protocols. The goal is to achieve complete control and protection from the environmental noise of the NV-spin state, incorporating quantum memories and logical operations to reach radiofrequency sensitivities well beyond those of classical NMR sensors. The quantum-enhanced benchtop NMR spectrometer will be applied and validated in an analytical chemistry lab environment to demonstrate record sensitivities in molecular analysis enabled by quantum technology, with potential applications in quality control, environmental monitoring, medical diagnostics, online monitoring of chemical reactors, and materials discovery.
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
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Keywords
Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)
Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)
Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
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HORIZON.2.4 - Digital, Industry and Space
MAIN PROGRAMME
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HORIZON.2.4.7 - Advanced Computing and Big Data
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Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
HORIZON-RIA - HORIZON Research and Innovation Actions
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Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
(opens in new window) HORIZON-CL4-2023-DIGITAL-EMERGING-01-CNECT
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Net EU financial contribution. The sum of money that the participant receives, deducted by the EU contribution to its linked third party. It considers the distribution of the EU financial contribution between direct beneficiaries of the project and other types of participants, like third-party participants.
80333 Muenchen
Germany
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.