Developing broad-spectrum antiviral drugs for pandemic preparedness

Project Information

PANVIPREP

Grant agreement ID: 101137229

DOI

10.3030/101137229

EC signature date 11 December 2023

Start date 1 January 2024

End date 31 December 2027

Funded under

• Health

Total cost

€ 7 999 298,25

EU contribution

€ 7 999 295,00

Coordinated by

ACADEMISCH ZIEKENHUIS LEIDEN
Netherlands

CORDIS provides links to public deliverables and publications of HORIZON projects.

Links to deliverables and publications from FP7 projects, as well as links to some specific result types such as dataset and software, are dynamically retrieved from OpenAIRE .

Deliverables

Websites, patent fillings, videos etc. (1)

PANVIPREP Web site

the launch of the project's web site

Documents, reports (1)

Data Management Plan Extern

The data management plan external report accepted by all participants

Other (1)

Project Boards and Committees

Project Boards and Committees - Setting up the project management office and boards (SAB, EIPC, EAB)

Publications

Peer reviewed articles (4)

The Combination of GS-441524 (Remdesivir) and Ribavirin Results in a Potent Antiviral Effect Against Human Parainfluenza Virus 3 Infection in Human Airway Epithelial Cell Cultures and in a Mouse Infection Model

Author(s): Yuxia Lin, Birgit Weynand, Xin Zhang, Manon Laporte, Dirk Jochmans, Johan Neyts
Published in: Viruses, Issue 17, 2025, ISSN 1999-4915
Publisher: MDPI AG
DOI: 10.3390/V17020172

A robust mouse model of HPIV-3 infection and efficacy of GS-441524 against virus-induced lung pathology

Author(s): Yuxia Lin, Mona Khan, Birgit Weynand, Manon Laporte, Frank Coenjaerts, Darius Babusis, John P. Bilello, Peter Mombaerts, Dirk Jochmans, Johan Neyts
Published in: Nature Communications, Issue 15, 2024, ISSN 2041-1723
Publisher: Springer Science and Business Media LLC
DOI: 10.1038/S41467-024-52071-5

A coronavirus assembly inhibitor that targets the viral membrane protein

Author(s): Manon Laporte, Dirk Jochmans, Dorothée Bardiot, Lowiese Desmarets, Oliver J. Debski-Antoniak, Giulia Mizzon, Rana Abdelnabi, Pieter Leyssen, Winston Chiu, Zhikuan Zhang, Norimichi Nomura, Sandro Boland, Umeharu Ohto, Yannick Stahl, Jurgen Wuyts, Steven De Jonghe, Annelies Stevaert, Martijn J. van Hemert, Brenda W. Bontes, Patrick Wanningen, G. J. Mirjam Groenewold, Aneta Zegar, Katarzyna Owczarek, Sanjata Joshi, Mohamed Koukni, Philippe Arzel, Hugo Klaassen, Jean-Christophe Vanherck, Ilse Vandecaetsbeek, Niels Cremers, Kim Donckers, Thibault Francken, Tina Van Buyten, Jasper Rymenants, Joost Schepers, Krzysztof Pyrc, Rolf Hilgenfeld, Jean Dubuisson, Berend-Jan Bosch, Frank Van Kuppeveld, Cecilia Eydoux, Etienne Decroly, Bruno Canard, Lieve Naesens, Birgit Weynand, Eric J. Snijder, Sandrine Belouzard, Toshiyuki Shimizu, Ralf Bartenschlager, Daniel L. Hurdiss, Arnaud Marchand, Patrick Chaltin, Johan Neyts
Published in: Nature, Issue 640, 2025, ISSN 0028-0836
Publisher: Springer Science and Business Media LLC
DOI: 10.1038/S41586-025-08773-X

Revealing protein structures: crystallization of protein‐ligand complexes – co‐crystallization and crystal soaking

Author(s): Barbora Kaščáková, Anna Koutská, Michaela Burdová, Petra Havlíčková, Ivana Kutá Smatanová
Published in: FEBS Open Bio, Issue 15, 2025, ISSN 2211-5463
Publisher: Wiley
DOI: 10.1002/2211-5463.13913