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Cohort Network To be Activated Globally In Outbreaks

Project description

Sustainable cohorts for re-emerging infectious diseases

The resurgence of infectious diseases in low- and middle-income countries (LMICs) presents a significant challenge. Observational cohorts play a crucial role in comprehending the natural history of diseases, including transmission routes, risk factors, and severe outcomes, thereby aiding in the design of intervention studies. The EU-funded CONTAGIO project brings together investigators from various regions to establish coordination mechanisms for rapid responses to the emergence or re-emergence of infectious diseases in LMICs. Leveraging insights from previous EU-funded projects, CONTAGIO aims to develop a preparedness and interoperability platform, data-sharing tools, and a governance framework. The project will explore how ongoing cohorts can adapt their focus during epidemics, creating a framework for the sustainable role of cohorts in preparedness during inter-epidemic periods.

Objective

CONTAGIO is a consortium of investigators from Europe, North America, Latin America, Asia, and Africa, that aims to create coordination mechanisms to rapidly react to infectious disease (re-)emergence in low- and middle-income countries (LMICs). The Consortium builds on the experience acquired through the EC-funded projects ReCoDiD, ORCHESTRA, ZIKAlliance, and IDAMS.
We believe that observational cohorts are essential instruments as they provide much needed information on the natural history of the disease, including transmission routes, vulnerability factors, the proportion of, and risk factors for, severe disease outcomes and therefore lay the ground for intervention studies.
CONTAGIO will convene cohort investigators and data/specimen sharing specialists by a) generating a preparedness and interoperability platform (WP1/2); b) enabling a suite of tools and key pathways for data sharing (WP2/3); and c) developing governance for sharing of biological material in the event of emerging infections (WP4). A key step on this path is the investigation of how ongoing cohorts ‘repurpose’ their focus from one infectious disease to another in the event of epidemics (e.g. from dengue to Zika to COVID-19).
The open science foreseen in CONTAGIO will create a coordination mechanism and framework for the role of sustainable cohorts in preparedness for (re-)emerging infectious diseases during interepidemic periods, which will be vital for the joint progress towards a better tackling of disease emergence aimed at the protection of citizens in LMICs, Europe and the rest of the world.

Fields of science (EuroSciVoc)

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Keywords

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Programme(s)

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Topic(s)

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Funding Scheme

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HORIZON-CSA - HORIZON Coordination and Support Actions

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Call for proposal

Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.

(opens in new window) HORIZON-HLTH-2023-DISEASE-03

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Coordinator

UNIVERSITATSKLINIKUM HEIDELBERG
Net EU contribution

Net EU financial contribution. The sum of money that the participant receives, deducted by the EU contribution to its linked third party. It considers the distribution of the EU financial contribution between direct beneficiaries of the project and other types of participants, like third-party participants.

€ 571 997,50
Address
IM NEUENHEIMER FELD 672
69120 HEIDELBERG
Germany

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Region
Baden-Württemberg Karlsruhe Heidelberg, Stadtkreis
Activity type
Higher or Secondary Education Establishments
Links
Total cost

The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.

€ 577 622,50

Participants (13)

Partners (2)

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