Prediction, Monitoring and Personalized Recommendations for Prevention and Relief of Dementia and Frailty

Project Information

COMFORTAGE

Grant agreement ID: 101137301

DOI

10.3030/101137301

EC signature date 7 December 2023

Start date 1 January 2024

End date 31 December 2027

Funded under

• Health

Total cost

€ 17 591 490,00

EU contribution

€ 17 591 490,00

Coordinated by

UNIVERSITY OF PIRAEUS RESEARCH CENTER
Greece

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Links to deliverables and publications from FP7 projects, as well as links to some specific result types such as dataset and software, are dynamically retrieved from OpenAIRE .

Deliverables

Documents, reports (25)

DEMB.C1 Clinical Study Approvals and Other Preparatory Procedures

Reporting that all the required approvals (e.g., regulatory, ethical, data access, material transfer agreements) have been obtained in the context of DEMB.C1 Clinical study

Exploitation, Market analysis & Sustainable Business Models I

Documenting the exploitation activities

Virtual assistants & AAL I

Describes the aspects of virtual assistants and AAL

FRA.C1 Clinical Study Approvals and Other Preparatory Procedures

Reporting that all the required approvals (e.g., regulatory, ethical, data access, material transfer agreements) have been obtained in the context of FRA.C1 Clinical study

DEMA.C1 Clinical Study Approvals and Other Preparatory Procedures

Reporting that all the required approvals (e.g., regulatory, ethical, data access, material transfer agreements) have been obtained in the context of DEMA.C1 Clinical study

People-Centred System Design I

Describes collective intelligence processes

Integrated AI-based Care Model Library I

Introduces the AI-based care models & Library

State of the art and requirements analysis II

SotA analysis & definition of project’s requirements

Coordination and co-design of pilot scenarios I

Identification and co-creation of pilot studies

State of the art and requirements analysis I

SotA analysis & definition of project’s requirements

Ethics requirements, guidelines, and best practices for trustworthy AI I

Assessment & recommendations on ethical aspects of AI

Digital Twins for Personalised Treatment and Monitoring I

Analysis and report of the Patient Digital Twins

Communication and Dissemination plan

Initial communication & dissemination planning. The website, its content and structuring will be also a key outcome of this deliverable.

Dissemination, Standardization & Joint Activities Report I

Report on the outcomes of T8.1 and T8.2

DEMA.C2 Clinical Study Approvals and Other Preparatory Procedures

Reporting that all the required approvals (e.g., regulatory, ethical, data access, material transfer agreements) have been obtained in the context of DEMA.C2 Clinical study

Social activation through Advanced Social Learning I

Analysis of advanced social learning mechanisms

COMFORTAGE Community and Ecosystem Building I

Activities & impact of project ecosystem

Clinical DSS Suite & Visual Analytic Tools I

Describes the different aspects of the DSS suite

COMFORTAGE Community and Ecosystem Building II

Activities & impact of project ecosystem

Secure Decentralized and Big Data Management I

Architect IKBs & Blockchain

Ageing-EHDS Data Space I

Project’s data space

Cognitive stimulation & physical empowerment tools I

Report on AI-based tools for cognitive stimulation

Training and Educational Toolkit I

Analysis and evaluation of the project’s TET

Data Modelling and Holistic Health Records I

Specification of HHR standard & model

Person-centric and behavioural change applications I

Describes the different user centric applications

Other (2)

Digital Healthcare Reference Model I

Project’s research reference model

Reference Architecture and Integration of VHP Platform I

Definition of components & their integration

Data Management Plan (1)

Data Management Plan I

Project’s DMP

Publications

Peer reviewed articles (3)

Investigating causal networks of dementia using causal discovery and natural language processing models

Author(s): Yu, Xinzhu; Lophatananon, Artitaya; Holmes, Vivien; Muir, Kenneth; Guo, Hui
Published in: npj Dementia, 2025, ISSN 3005-1940
Publisher: Nature
DOI: 10.1038/S44400-025-00006-2

Exploring the Relationships between Lifestyle Patterns and Epigenetic Biological Age Measures in Men

Author(s): Ke, Te-Min; Lophatananon, Artitaya; Muir, Kenneth R
Published in: Biomedicines, 2024, ISSN 2227-9059
Publisher: MDPI
DOI: 10.3390/BIOMEDICINES12091985

Establishing a Digitally Enabled Healthcare Framework for Enhanced Prevention, Risk Identification, and Relief for Dementia and Frailty

Author(s): Manias G, Likothanassis S, Alexakis E, Antoniades A, Marra C, Giuffrè GM, Charalambous E, Tsolis D, Tsirogiannis G, Koutsomitropoulos D, et al.
Published in: Journal of Dementia and Alzheimer's Disease, 2025, ISSN 3042-4518
Publisher: MDPI
DOI: 10.3390/JDAD2030030

Conference proceedings (8)

Improved Explainability on Clinical Settings Through the Utilization of an Advanced Explainable Dashboard Hub

Author(s): George Manias, Eleftheria Kouremenou, Ainhoa Azqueta-Alzúaz, Emmanouil Alexakis, Spyridon Kleftakis, Dimosthenis Kyriazis
Published in: IFIP Advances in Information and Communication Technology, Artificial Intelligence Applications and Innovations. AIAI 2025 IFIP WG 12.5 International Workshops, 2025
Publisher: Springer Nature Switzerland
DOI: 10.1007/978-3-031-97313-0_17

Digital Twins in Older Adults’ Mental Healthcare: A Literature Review

Author(s): Stylianos Kokkas, Sofia Segkouli, Konstantinos Votis
Published in: IFIP Advances in Information and Communication Technology, Artificial Intelligence Applications and Innovations. AIAI 2025 IFIP WG 12.5 International Workshops, 2025
Publisher: Springer Nature Switzerland
DOI: 10.1007/978-3-031-97313-0_15

Aligning Clinical Workflows and AI Integration: Digital Healthcare Reference Model in Dementia and Frailty Care

Author(s): Mirella Sangiovanni, Nemania Borovits, George Manias, Willem-Jan van den Heuvel
Published in: Lecture Notes in Business Information Processing, Business Modeling and Software Design, 2025
Publisher: Springer Nature Switzerland
DOI: 10.1007/978-3-031-98033-6_20

Early Detection and Prevention of Dementia: An AI-Driven Multimodal Approach

Author(s): Andy Huang, George Manias, Renato Cordeiro Ferreira, Mirella Sangiovanni, Nemania Borovits, Damian A. Tamburri, Eva Ntanasi, Nikolaos Scarmeas, Willem-Jan van den Heuvel
Published in: IFIP Advances in Information and Communication Technology, Artificial Intelligence Applications and Innovations. AIAI 2025 IFIP WG 12.5 International Workshops, 2025
Publisher: Springer Nature Switzerland
DOI: 10.1007/978-3-031-97313-0_16

The ETHAI Methodology

Author(s): Lorena Volpini, Valerio Prosseda, Francesca Morpurgo, Špela Glišovic Krivec, David Krivec
Published in: IFIP Advances in Information and Communication Technology, Artificial Intelligence Applications and Innovations. AIAI 2025 IFIP WG 12.5 International Workshops, 2025
Publisher: Springer Nature Switzerland
DOI: 10.1007/978-3-031-97313-0_19

Conceptualization and Functional Specifications of an e-learning Ecosystem Towards the Support of Older Adults and Their Supports in Developing Digital and Health Literacy Skills

Author(s): Antonios Billis, Despoina Mantziari, Vasiliki Kalfa, Emmanouil Rigas, Styliani-Olympia Tsormpatzoudi, Maria Karagianni, Konstantinos Diamantis, Panagiotis D. Bamidis
Published in: IFIP Advances in Information and Communication Technology, Artificial Intelligence Applications and Innovations. AIAI 2025 IFIP WG 12.5 International Workshops, 2025
Publisher: Springer Nature Switzerland
DOI: 10.1007/978-3-031-97313-0_14

Enhancing Federated Learning with SOA: An Approach to Tackle Non-IID Data Challenges

Author(s): Loukas Papadopoulos, Nemania Borovits, George Manias, Damian Andrew Tamburri, Willem-Jan Van Den Heuvel
Published in: Lecture Notes in Computer Science, Service-Oriented Computing – ICSOC 2024 Workshops, 2025
Publisher: Springer Nature Singapore
DOI: 10.1007/978-981-96-7238-7_14

On the Maturity of LLMOps Services Computing: An Industrial Study

Author(s): Nemania Borovits, Damian A. Tamburri, Willem-Jan van den Heuvel
Published in: Lecture Notes in Business Information Processing, Advanced Information Systems Engineering Workshops, 2025
Publisher: Springer Nature Switzerland
DOI: 10.1007/978-3-031-94931-9_25