Deconstructing the protective immunity of yellow fever virus 17D to inform flavivirus vaccine design

Project Information

Yellow4FLAVI

Grant agreement ID: 101137459

DOI

10.3030/101137459

EC signature date 14 November 2023

Start date 1 January 2024

End date 31 December 2028

Funded under

• Health

Total cost

€ 8 544 780,75

EU contribution

€ 8 544 780,75

Coordinated by

INSTITUT PASTEUR
France

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Deliverables

Documents, reports (3)

Training plan
Project management handbook
Dissemination and Communication Plan

Websites, patent fillings, videos etc. (1)

Project website

Publications

Peer reviewed articles (8)

YF17D‐based vaccines – standing on the shoulders of a giant

Author(s): Lorena Sanchez‐Felipe, Yeranddy A. Alpizar, Ji Ma, Lotte Coelmont, Kai Dallmeier
Published in: European Journal of Immunology, Issue 54, 2024, ISSN 0014-2980
Publisher: Wiley
DOI: 10.1002/EJI.202250133

T cell-mediated protection in absence of virus neutralizing antibodies

Author(s): Yeranddy A. Alpizar, Kai Dallmeier
Published in: Nature Microbiology, Issue 10, 2025, ISSN 2058-5276
Publisher: Springer Science and Business Media LLC
DOI: 10.1038/S41564-024-01921-5

Basal T cell activation predicts yellow fever vaccine response independently of cytomegalovirus infection and sex-related immune variations

Author(s): Antonio Santos-Peral, Magdalena Zaucha, Elena Nikolova, Ekin Yaman, Barbara Puzek, Elena Winheim, Sebastian Goresch, Magdalena K. Scheck, Lisa Lehmann, Frank Dahlstroem, Hadi Karimzadeh, Julia Thorn-Seshold, Shenzhi Jia, Fabian Luppa, Michael Pritsch, Julia Butt, Camila Metz-Zumaran, Giovanna Barba-Spaeth, Stefan Endres, Sarah Kim-Hellmuth, Tim Waterboer, Anne B. Krug, Simon Rothenfusser
Published in: Cell Reports Medicine, Issue 6, 2025, ISSN 2666-3791
Publisher: Elsevier BV
DOI: 10.1016/J.XCRM.2025.101946

Nature Communications

Author(s): Antonio Santos-Peral; Fabian Luppa; Sebastian Goresch; Elena Nikolova; Magdalena Zaucha; Lisa Lehmann; Frank Dahlstroem; Hadi Karimzadeh; Julia Thorn-Seshold; Elena Winheim; Ev-Marie Schuster; Gerhard Dobler; Michael Hoelscher; Beate M. Kümmerer; Stefan Endres; Kilian Schober; Anne B. Krug; Michael Pritsch; Giovanna Barba-Spaeth; Simon Rothenfusser
Published in: Nature Communications, Vol 15, Iss 1, Pp 1-17 (2024), Issue 15, 2024, ISSN 2041-1723
Publisher: Springer Nature
DOI: 10.1038/s41467-024-45806-x

Nature Communications

Author(s): Santos-Peral, Antonio; Luppa, Fabian; Goresch, Sebastian; Nikolova, Elena; Zaucha, Magdalena; Lehmann, Lisa; Dahlstroem, Frank; Karimzadeh, Hadi; Thorn-Seshold, Julia; Winheim, Elena; Schuster, Ev-Marie; Dobler, Gerhard; Hoelscher, Michael; Kümmerer, Beate; Endres, Stefan; Schober, Kilian; Krug, Anne; Pritsch, Michael; Barba-Spaeth, Giovanna; Rothenfusser, Simon
Published in: Nature Communications, 2024, ISSN 2041-1723
Publisher: Springer Nature
DOI: 10.1038/S41467-024-45806-X

Toward a deeper understanding of dengue: novel method for quantification and isolation of envelope protein epitope-specific antibodies

Author(s): Sokchea Lay, Candice Bohaud, Sopheak Sorn, Sreymom Ken, Felix A. Rey, Kevin K. Ariën, Sowath Ly, Veasna Duong, Giovanna Barba-Spaeth, Heidi Auerswald, Tineke Cantaert
Published in: mSphere, 2025, ISSN 2379-5042
Publisher: American Society for Microbiology
DOI: 10.1128/MSPHERE.00961-24

Interferon-induced activation of dendritic cells and monocytes by yellow fever vaccination correlates with early antibody responses

Author(s): Elena Winheim, Antonio Santos-Peral, Tamara Ehm, Linus Rinke, Sandra Riemer, Magdalena Zaucha, Sebastian Goresch, Lisa Lehmann, Katharina Eisenächer, Michael Pritsch, Giovanna Barba-Spaeth, Tobias Straub, Simon Rothenfusser, Anne B. Krug
Published in: Proceedings of the National Academy of Sciences, Issue 122, 2025, ISSN 0027-8424
Publisher: Proceedings of the National Academy of Sciences
DOI: 10.1073/PNAS.2422236122

Multiplexed multicolor antiviral assay amenable for high-throughput research

Author(s): Li-Hsin Li, Winston Chiu, Yun-An Huang, Madina Rasulova, Thomas Vercruysse, Hendrik Jan Thibaut, Sebastiaan ter Horst, Joana Rocha-Pereira, Greet Vanhoof, Doortje Borrenberghs, Olivia Goethals, Suzanne J. F. Kaptein, Pieter Leyssen, Johan Neyts, Kai Dallmeier
Published in: Nature Communications, Issue 15, 2024, ISSN 2041-1723
Publisher: Springer Science and Business Media LLC
DOI: 10.1038/S41467-023-44339-Z