Project description
CERN technology for medical applications
Medical imaging technologies are constantly evolving, offering new ways to improve cancer treatment and surgery. One promising innovation is i-TED, a highly sensitive gamma-ray imaging technology originally developed for nuclear astrophysics experiments at CERN. One of its key advantages is its ability to filter out background noise, making it a strong candidate for medical applications. The ERC-funded AMA project will explore how i-TED can be employed to improve two areas of healthcare: guiding surgeons during cancer-related procedures and monitoring radiation doses in emerging cancer treatments based on neutron capture. Researchers will conduct proof-of-concept studies to demonstrate the potential benefits of the technology and evaluate its readiness for clinical use.
Objective
i-TED is a gamma-ray imaging system that was fully developed and successfully applied for nuclear astrophysics experiments at CERN n_TOF in the previous HYMNS ERC CoG. i-TED was designed for highest possible detection sensitivity, and it is also characterized by its modularity, portability and low sensitivity to neutron-induced backgrounds. These characteristics make the developed system potentially very attractive for several emerging applications in health and life science. Indeed, Compton imagers are expected to provide a breakthough innovation potential in the fields of i) ion-range monitoring in hadron therapy, ii) intraoperative Radio-Guided Surgery (RGS), iii) dose-monitoring in boron-neutron capture therapy (BNCT), and iv) theranostics (radioisotopes that serve for both therapy and diagnostics). Thus, the aim of this POC proposal is to perform first proof-of-concept measurements with readily available i-TED Compton cameras for demonstrating their applicability and advantages in two of these fields: (ii) intraoperative RGS and (iii) neutron dose assessment in BNCT. We also aim at addressing the corresponding technical-readiness levels (TRLs) for each application, which seems the most convenient approach for an efficient transfer of the developed technology towards society.
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: https://op.europa.eu/en/web/eu-vocabularies/euroscivoc.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: https://op.europa.eu/en/web/eu-vocabularies/euroscivoc.
- medical and health sciences clinical medicine surgery
- engineering and technology electrical engineering, electronic engineering, information engineering electronic engineering sensors optical sensors
- natural sciences physical sciences astronomy astrophysics
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Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
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HORIZON.1.1 - European Research Council (ERC)
MAIN PROGRAMME
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Topic(s)
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Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
HORIZON-ERC-POC - HORIZON ERC Proof of Concept Grants
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Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
(opens in new window) ERC-2023-POC
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Net EU financial contribution. The sum of money that the participant receives, deducted by the EU contribution to its linked third party. It considers the distribution of the EU financial contribution between direct beneficiaries of the project and other types of participants, like third-party participants.
28006 MADRID
Spain
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.