Integrated Models for the Development and Assessment of High Impact Chemicals and Materials

Project Information

INSIGHT

Grant agreement ID: 101137742

DOI

10.3030/101137742

EC signature date 7 December 2023

Start date 1 January 2024

End date 31 December 2027

Funded under

• Digital, Industry and Space

Total cost

€ 4 130 318,75

EU contribution

€ 4 130 318,75

Coordinated by

TAMPEREEN KORKEAKOULUSAATIO SR
Finland

CORDIS provides links to public deliverables and publications of HORIZON projects.

Links to deliverables and publications from FP7 projects, as well as links to some specific result types such as dataset and software, are dynamically retrieved from OpenAIRE .

Deliverables

Documents, reports (8)

Outreach and Training Plan
Case study specifications and roadmap of the modelling and data requirements
Organisation of the Kick-off meeting & Initial Project Documentation and Resources
Short Interim Management Report 1

A short summary (max 5 pages) with the following elements:• The objective for the period• Progress obtained and outcome • Issues encounter and challenges to address forward

Report on the compendium of models
Project Quality Management & Management Plan
Report on Data Gap Analysis
Project Internal Ethical Guideline

Websites, patent fillings, videos etc. (1)

INSIGHT Corporate Identity (project logo, website, brochure, poster)

Publications

Peer reviewed articles (11)

The FAIR principles as a key enabler to operationalize safe and sustainable by design approaches

Author(s): Achilleas Karakoltzidis, Chiara Laura Battistelli, Cecilia Bossa, Evert A. Bouman, Irantzu Garmendia Aguirre, Ivo Iavicoli, Maryam Zare Jeddi, Spyros Karakitsios, Veruscka Leso, Magnus Løfstedt, Barbara Magagna, Denis Sarigiannis, Erik Schultes, Lya G. Soeteman-Hernández, Vrishali Subramanian, Penny Nymark
Published in: RSC Sustainability, Issue 2, 2024, ISSN 2753-8125
Publisher: Royal Society of Chemistry (RSC)
DOI: 10.1039/D4SU00171K

Single-cell RNA sequencing uncovers heterogenous immune cell responses upon exposure to food additive (E171) titanium dioxide

Author(s): Perumalsamy, Haribalan; Xiao, Xiao; Han, Hyoung-Yun; Oh, Jung-Hwa; Yoon, Seokjoo; Heo, Min Beom; Lee, Tae Geol; Kim, Hyun-Yi; Yoon, Tae-Hyun
Published in: Journal of Nanobiotechnology, 2024, ISSN 0000-0000
Publisher: Springer Nature
DOI: 10.1186/S12951-024-03036-9

Wisdom of Crowds for Supporting the Safety Evaluation of Nanomaterials

Author(s): Laura Aliisa Saarimäki; Michele Fratello; Giusy del Giudice; Emanuele Di Lieto; Antreas Afantitis; Harri Alenius; Eliodoro Chiavazzo; Mary Gulumian; Piia Karisola; Iseult Lynch; Giulia Mancardi; Georgia Melagraki; Paolo Netti; Anastasios G. Papadiamantis; Willie Peijnenburg; Hélder A Santos; Tommaso Serchi; Mohammad-Ali Shahbazi; Tobias Stoeger; Eugenia Valsami-Jones; Paola Vivo; Ivana Vinković Vrček; Ulla Vogel; Peter Wick; David A. Winkler; Angela Serra; Dario Greco
Published in: Environmental Science & Technology, 2025, ISSN 0000-0000
Publisher: ACS Publications
DOI: 10.2139/SSRN.5066370

Quantum Dot‐Based Immunolabelling of Extracellular Vesicles and Detection Using Fluorescence‐Based Nanoparticle Tracking Analysis

Author(s): Ha, Eunyong; Han, Yewon; Kim, Minseop; Gerelkhuu, Zayakhuu; Kwon, Sook Jin; Yoon, Tae Hyun
Published in: Journal of Extracellular Biology, 2025, ISSN 0000-0000
Publisher: Wiley Periodicals LLC
DOI: 10.1002/JEX2.70072

Nanomaterial grouping: Unraveling the relationship of induced mechanisms and potency at a temporal scale

Author(s): Marcella Torres Maia, Michele Fratello, Giusy del Giudice, Laura Aliisa Saarimäki, Lena Möbus, Angela Serra, Dario Greco
Published in: Nano Today, Issue 61, 2025, ISSN 1748-0132
Publisher: Elsevier BV
DOI: 10.1016/J.NANTOD.2025.102639

A composite indicator for evaluating safety and sustainability by design and circularity in emerging technologies

Author(s): Arias Calvo, A.; Cinelli, M.; Moreira, M.T.; Cucurachi, S.
Published in: Sustainable Production and Consumption, 2024, ISSN 2352-5509
Publisher: sciencedirect
DOI: 10.1016/J.SPC.2024.09.027

A systems biology approach to understand temporal evolution of silver nanoparticle toxicity

Author(s): Park, Seung-Geun; Lee, Eunseo; Kim, Hyun-Yi; Yoon, Tae Hyun
Published in: npj Systems Biology and Applications, 2025, ISSN 2056-7189
Publisher: Nature
DOI: 10.1038/S41540-025-00561-7

A Network Toxicology Approach for Mechanistic Modelling of Nanomaterial Hazard and Adverse Outcomes

Author(s): Giusy del Giudice, Angela Serra, Alisa Pavel, Marcella Torres Maia, Laura Aliisa Saarimäki, Michele Fratello, Antonio Federico, Harri Alenius, Bengt Fadeel, Dario Greco
Published in: Advanced Science, Issue 11, 2024, ISSN 2198-3844
Publisher: Wiley
DOI: 10.1002/ADVS.202400389

INSIGHT: An integrated framework for safe and sustainable chemical and material assessment

Author(s): Angela Serra; Dimitrios Zouraris; Alexandra Schaffert; Marcella Torres Maia; Periklis Tsiros; Ishita Virmani; Emanuele Di Lieto; Laura Aliisa Saarimäki; Jack Morikka; Rafael Riudavets-Puig; Dimitra-Danai Varsou; Konstantinos D. Papavasileiou; Panagiotis D. Kolokathis; Dimitris G. Mintis; Haralampos Tzoupis; Andreas Tsoumanis; Georgia Melagraki; Alex Arvanitidis; Philip Doganis; Vasileios Minadakis; Giannis Savvas; Adrien Perello-y-bestard; Stefano Cucurachi; Marija Buljan; Fotini Nikiforou; Achilleas Karakoltzidis; Spyros Karakitsios; Dimosthenis A. Sarigiannis; Steffi Friedrichs; Christian Seitz; Tomas Navarrete Gutierrez; Panagiotis Isigonis; Sébastien Cambier; Antonino Marvuglia; Gottlieb Georg Lindner; Jacques-Aurélien Sergent; L. Cristiana Gheorghe; Laura-Jayne A. Bradford; Seung-Geun Park; Seung Min Ha; Zayakhuu Gerelkhuu; Tae Hyun Yoon; Romana Petry; Diego Stéfani Teodoro Martinez; David A. Winkler; Peter Wick; Thomas E. Exner; Francesco Dondero; Tommaso Serchi; Willie Peijnenburg; Haralambos Sarimveis; Martin Paparella; Iseult Lynch; Antreas Afantitis; Dario Greco
Published in: Computational and Structural Biotechnology Journal, 2025, ISSN 0000-0000
Publisher: Elsevier B.V.
DOI: 10.1016/J.CSBJ.2025.03.042

Easy-MODA: Simplifying standardised registration of scientific simulation workflows through MODA template guidelines powered by the Enalos Cloud Platform

Author(s): Panagiotis D. Kolokathis, Nikolaos K. Sidiropoulos, Dimitrios Zouraris, Dimitra-Danai Varsou, Dimitris G. Mintis, Andreas Tsoumanis, Francesco Dondero, Thomas E. Exner, Haralambos Sarimveis, Evgenia Chaideftou, Martin Paparella, Fotini Nikiforou, Achilleas Karakoltzidis, Spyros Karakitsios, Dimosthenis Sarigiannis, Jesper Friis, Gerhard Goldbeck, David A. Winkler, Willie Peijnenburg, Angela Serra, Dario Greco, Georgia Melagraki, Iseult Lynch, Antreas Afantitis
Published in: Computational and Structural Biotechnology Journal, Issue 25, 2024, ISSN 2001-0370
Publisher: Elsevier BV
DOI: 10.1016/J.CSBJ.2024.10.018

AI-based nanotoxicity data extraction and prediction of nanotoxicity

Author(s): Ha, Eunyong; Ha, Seung Min; Gerelkhuu, Zayakhuu; Kim, Hyun-Yi; Yoon, Tae Hyun
Published in: Computational and Structural Biotechnology Journal, 2025, ISSN 0000-0000
Publisher: Elsevier B.V.
DOI: 10.1016/J.CSBJ.2025.03.052