Project description
Patient-specific models for pancreatic cancer
Pancreatic cancer is a highly aggressive and often fatal cancer, with a low 5-year survival rate due to late diagnosis and limited effective treatment options. To develop effective, targeted therapies there is a need for reliable ex vivo models that accurately replicate tumour biology and cell interactions. The ERC-funded Design2Guide project aims to address the high mortality rate of pancreatic cancer by developing a novel platform for patient-specific models. This controllable laboratory platform will enable researchers to better understand pancreatic cancer and identify more effective treatments. By mimicking the complex interactions within tumours, Design2Guide seeks to uncover new therapeutic strategies, ultimately improving treatment outcomes for patients with this devastating disease.
Objective
This research addresses a clinical problem with an innovative approach. Pancreatic cancer is one of the deadliest cancers and only 10% of patients survive 5 years after diagnosis. To find better therapies, we need patient-specific models that mimic the biology of tumour tissues and target interactions between different cell types. We will develop a controllable platform for modelling the human disease in the laboratory. We will use our new platform to discover better ways of treating the disease.
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
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Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
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HORIZON.1.1 - European Research Council (ERC)
MAIN PROGRAMME
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Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
HORIZON-ERC-POC - HORIZON ERC Proof of Concept Grants
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Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
(opens in new window) ERC-2023-POC
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Net EU financial contribution. The sum of money that the participant receives, deducted by the EU contribution to its linked third party. It considers the distribution of the EU financial contribution between direct beneficiaries of the project and other types of participants, like third-party participants.
01069 Dresden
Germany
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.