The ReGreeneration project emerges in response to the urgent need to transform urban environments into more resilient, inclusive, and sustainable spaces, aligning with European strategic objectives regarding climate adaptation, social cohesion, and urban regeneration. In this context, the project articulates a series of pilot interventions in European cities, combining digital tools, participatory methodologies, and nature-based solutions to address local challenges such as environmental degradation, social exclusion, and the lack of quality public spaces. Through an interdisciplinary work structure that integrates social sciences, humanities, technology, and urban planning, ReGreeneration promotes co-creation with citizens, the involvement of local economic stakeholders, and impact assessment through key performance indicators (KPIs). The project's results are expected to generate significant impacts at the local and European scales, both in terms of improving urban well-being and in the formulation of replicable policies, thus contributing to a structural transformation of contemporary urban development models.