Preventing Bone Loss by Targeting Endothelial Cell-Tissue Crosstalk

Project Information

PROTECT

Grant agreement ID: 101139772

DOI

10.3030/101139772

EC signature date 27 May 2024

Start date 1 June 2024

End date 31 May 2029

Funded under

• European Research Council (ERC)

Total cost

€ 2 498 719,00

EU contribution

€ 2 498 719,00

Coordinated by

MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV
Germany

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Links to deliverables and publications from FP7 projects, as well as links to some specific result types such as dataset and software, are dynamically retrieved from OpenAIRE .

Deliverables

Data Management Plan (1)

Research Data Management

Drafting of Data Management Plan

Publications

Peer reviewed articles (5)

Three-dimensional quantitative tissue clearing reveals differences in osteovascular niche of aged and young human mesenchymal stromal cells

Author(s): Nelson Tsz Long Chu, Ostap Dregval, Yu-Wei Chang, Emil Kriukov, Xin Tian, Xin Liu, Dana Trompet, Misty Shuo Zhang, Lei Li, Zhong Li, Emiliano Gomez Ruiz, Joana B. Pereira, Mats Brittberg, Björn Barenius, Lars Sävendahl, Ralf H. Adams, Inger Gjertsson, Claes Ohlsson, Giovanni Volpe, Andrei S. Chagin
Published in: Nature Biomedical Engineering, 2026, ISSN 2157-846X
Publisher: Springer Science and Business Media LLC
DOI: 10.1038/S41551-026-01645-3

Functional Specialization of the Calvarial Bone Marrow

Author(s): Bong Ihn Koh, Ralf H. Adams
Published in: Physiology, Issue 41, 2026, ISSN 1548-9213
Publisher: American Physiological Society
DOI: 10.1152/PHYSIOL.00028.2025

Specialized post-arterial capillaries facilitate adult bone remodelling

Author(s): Vishal Mohanakrishnan, Kishor K. Sivaraj, Hyun-Woo Jeong, Esther Bovay, Backialakshmi Dharmalingam, M. Gabriele Bixel, Van Vuong Dinh, Milena Petkova, Isidora Paredes Ugarte, Yi-Tong Kuo, Malarvizhi Gurusamy, Brian Raftrey, Nelson Tsz Long Chu, Soumyashree Das, Pamela E. Rios Coronado, Martin Stehling, Lars Sävendahl, Andrei S. Chagin, Taija Mäkinen, Kristy Red-Horse, Ralf H. Adams
Published in: Nature Cell Biology, Issue 26, 2024, ISSN 1465-7392
Publisher: Springer Science and Business Media LLC
DOI: 10.1038/S41556-024-01545-1

Adult skull bone marrow is an expanding and resilient haematopoietic reservoir

Author(s): Bong Ihn Koh, Vishal Mohanakrishnan, Hyun-Woo Jeong, Hongryeol Park, Kai Kruse, Young Jun Choi, Melina Nieminen-Kelhä, Rahul Kumar, Raquel S. Pereira, Susanne Adams, Hyuek Jong Lee, M. Gabriele Bixel, Peter Vajkoczy, Daniela S. Krause, Ralf H. Adams
Published in: Nature, Issue 636, 2024, ISSN 0028-0836
Publisher: Springer Science and Business Media LLC
DOI: 10.1038/S41586-024-08163-9

ELMO2 is an essential regulator of carotid artery development

Author(s): Athira Suresh, Kai Kruse, Hendrik Arf, Rodrigo Diéguez-Hurtado, Ralf H. Adams
Published in: Nature Communications, Issue 16, 2025, ISSN 2041-1723
Publisher: Springer Science and Business Media LLC
DOI: 10.1038/S41467-025-60105-9