Reconstitution of glycan-driven MHC-I recycling reveals calreticulin as mediator between TAPBPR and tapasin
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Autores:
Tim J Heinke, Amin Fahim, Niko Popovic, Tobias Rath, Ines K Müller, Nina Morgner, Simon Trowitzsch, Robert Tampé
Publicado en:
The EMBO Journal, 2026, ISSN 1460-2075
Editor:
Springer Science and Business Media LLC
DOI:
10.1038/S44318-026-00873-2
Quantitative nanoscale imaging shows peptide–MHC I complexes are monomeric and spatially regulated in human dendritic cells
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Autores:
Olivia Jacobs, Tanja Menche, Cindy Höper, Frédéric Gerhards, Ivica Fucek, Fulvia Vascotto, Marina S. Dietz, Mike Heilemann, Robert Tampé
Publicado en:
Proceedings of the National Academy of Sciences, Edición 123, 2026, ISSN 0027-8424
Editor:
National Academy of Sciences
DOI:
10.1073/PNAS.2615838123
Single-molecule dynamics reveal ATP binding alone powers substrate translocation by an ABC transporter
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Autores:
Christoph Nocker, Matija Pečak, Tobias Nocker, Amin Fahim, Lukas Sušac, Robert Tampé
Publicado en:
Nature Communications, Edición 17, 2026, ISSN 2041-1723
Editor:
Springer Science and Business Media LLC
DOI:
10.25716/GUDE.0FRP-685B
Architectural principles of transporter-chaperone coupling within the native MHC I peptide-loading complex
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Autores:
Milena Stolz, Lukas Sušac, Amin Fahim, Rieke Keller, Lisa Saggau, Filippo Mancia, Simon Trowitzsch, Robert Tampé
Publicado en:
Science Advances, Edición 12, 2026, ISSN 2375-2548
Editor:
American Association for the Advancement of Science (AAAS)
DOI:
10.1126/SCIADV.AEA7735
