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Maximizing the use of a first clinically viable MYC inhibitor

CORDIS provides links to public deliverables and publications of HORIZON projects.

Links to deliverables and publications from FP7 projects, as well as links to some specific result types such as dataset and software, are dynamically retrieved from OpenAIRE .

Publications

The leading role of MYC in DNA damage response: exploring opportunities for therapeutic inhibition (opens in new window)

Author(s): Fabio Giuntini, Jonathan R. Whitfield, Daniel Massó-Vallés, Laura Soucek
Published in: Frontiers in Cell and Developmental Biology, Issue 13, 2026, ISSN 2296-634X
Publisher: Frontiers Media SA
DOI: 10.3389/FCELL.2025.1726515

Nature Reviews Drug Discovery (opens in new window)

Author(s): Jonathan R. Whitfield; Laura Soucek
Published in: Nature Reviews Drug Discovery, 2025, ISSN 1474-1776
Publisher: Nature Publishing Group
DOI: 10.1038/S41573-025-01143-2

MYC inhibition by Omomyc causes DNA damage and overcomes PARPi resistance in breast cancer (opens in new window)

Author(s): Fabio Giuntini, Íñigo González-Larreategui, Andrea Herencia-Ropero, Silvia Casacuberta-Serra, Mariano F. Zacarías-Fluck, Magdalena Arnal, Flaminia Pedretti, Sandra Martínez-Martín, Hugo Thabussot, Virginia Castillo Cano, Judit Grueso, Laia Foradada, Erika Serrano, Sergio López-Estévez, Olga Rodriguez, Marta Guzman, Adela Rodriguez-Hernandez, Fara Brasó-Maristany, Alba Llop-Guevara, Judith Balmaña, Lara Nonell, Aleix Prat, Violeta Serra, Marie-Eve Beaulieu, Jonathan R. Whitfield, Daniel Massó-Vallés, Laura Soucek
Published in: Cell Reports, Issue 44, 2025, ISSN 2211-1247
Publisher: Elsevier BV
DOI: 10.1016/J.CELREP.2025.116604

MYC and KRAS cooperation: from historical challenges to therapeutic opportunities in cancer (opens in new window)

Author(s): Sílvia Casacuberta-Serra; Íñigo González-Larreategui; Daniel Capitán-Leo; Laura Soucek
Published in: Signal Transduction and Targeted Therapy, 2024, ISSN 2059-3635
Publisher: Nature Publishing Group
DOI: 10.1038/S41392-024-01907-Z

MYC at the tumor–immune interface: mechanisms of immune escape and immunotherapy resistance (opens in new window)

Author(s): Íñigo González-Larreategui, Manrique Valdés-Bango Martín, Sílvia Casacuberta-Serra, Laura Soucek
Published in: Frontiers in Immunology, Issue 17, 2026, ISSN 1664-3224
Publisher: Frontiers Media SA
DOI: 10.3389/FIMMU.2026.1738440

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