Objetivo
Osteoarthritis is a debilitating disease affecting the joint and a leading cause of disability worldwide. It affects at least 250m people and incurs healthcare costs of toward 0.5% of the GDP.
Peptinov is developing an active immunotherapy that can halt inflammation-driven destruction of the cartilage in the joints. We use a unique approach to neutralise a key pro-inflammatory protein (IL-6) driving chronic inflammation. Our vaccine-like approach stimulates the patient’s own immune system to produce antibodies against excess IL-6 and neutralise its biological function. By doing so we will halt disease progression.
Our treatment will cost 5-10% of conventional immunotherapies as we inject patients with inexpensive, immunogenic peptides to stimulate production of endogenous antibodies. Phase I clinical trial yielded very encouraging preliminary safety and tolerability data on 24 patients. This project will implement the Phase II clinical trial and make our therapy out-licensing ready.
Ámbito científico
Palabras clave
Programa(s)
- HORIZON.3.1 - The European Innovation Council (EIC) Main Programme
Convocatoria de propuestas
HORIZON-EIC-2023-ACCELERATOR-01
Consulte otros proyectos de esta convocatoriaRégimen de financiación
HORIZON-EIC-ACC-BF - HORIZON EIC Accelerator Blended FinanceCoordinador
75009 PARIS
Francia
Organización definida por ella misma como pequeña y mediana empresa (pyme) en el momento de la firma del acuerdo de subvención.