Objective
"Fluorinated motifs have enormous societal relevance due to their ubiquity across the pharmaceutical, agrochemical and materials science sectors. These essential structural components feature prominently in the World Health Organization’s (WHO) list of essential medicines, and contribute to global food supplies by optimising the performance of many key agrochemicals. Similarly, our reliance on (polyfluorinated) materials ranging from non-stick Teflon® through to smart materials underscores the versatility of fluorinated groups in functional small molecule design.
The historic success of fluorinated groups in societally-important molecules, coupled with scarcity of organofluorine building blocks in nature, continues to create a powerful impetus to develop more efficient and sustainable methods to facilitate their construction. However, the environmental impact of perfluorinated materials has come under scrutiny due to the persistence of the materials in the environment. The recent proposal by the European Parliament to address the persistence of perfluoroalkyl and polyfluoroalkyl (PFAS-type molecules) in water supplies covers ""any substance that contains at least one fully fluorinated methyl (CF3) or methylene (CF2) without any H, Cl, Br, or I attached to it.""
Fluorinated groups that simultaneously conform to new legislative guidance, no longer pose an environmental threat and open up new areas of space for discovery will be generated efficiently. Through the intervention of ChiroFluor, unique structural entities such as the BITE group will be forged in both enantiomeric forms (handedness) to push chemical space beyond the existing boundaries. This project will simultaneously address a pressing environmental and legislative issue in a sustainable manner using an organocatalytic I(I)/I(III) platform based on data generated in ERC Consolidator RECON (818949), and validated with key industrial partners.
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Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
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Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
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HORIZON.1.1 - European Research Council (ERC)
MAIN PROGRAMME
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Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
HORIZON-ERC-POC - HORIZON ERC Proof of Concept Grants
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Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
(opens in new window) ERC-2023-POC
See all projects funded under this callHost institution
Net EU financial contribution. The sum of money that the participant receives, deducted by the EU contribution to its linked third party. It considers the distribution of the EU financial contribution between direct beneficiaries of the project and other types of participants, like third-party participants.
48149 Muenster
Germany
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.