Project description
Revolutionary microscope for advancing dermatology and cosmetics
While working on the ERC REMINISCENCE project, the team developed a revolutionary microscope that surpassed expectations. Named DeepInsight, this device uses a reflection matrix approach to wave imaging, delivering unparalleled imaging performance. It offers non-invasive, label-free, real-time, 3D imaging of tissues with a penetration depth of 1 mm and resolution of 500 nm. Additionally, it enables quantitative tissue imaging through biomarker mapping. In this context, the ERC-funded MUSE project aims to better understand its capabilities and explore its potential applications in the cosmetics industry and dermatology sectors. Its utilisation could lead to earlier detection of melanomas, non-invasive angiographies for identifying skin diseases and other significant advancements in dermatology.
Objective
During the ERC REMINISCENCE project, we developed a new microscope whose performances exceed our initial expectations. Based on a reflection matrix approach of wave imaging, this device called DeepInsight provides an unprecedented imaging performance. It allows non-invasive, label-free, real-time and three-dimensional imaging of tissues with a 1 mm-penetration depth at a 500 nm-resolution. Beyond the structural information provided by standard reflectivity images, it also enables quantitative imaging of tissues by mapping biomarkers such as the refractive index, tissue dynamics or scattering strength. This patented innovation thus represents a paradigm shift in label-free microscopy. In the framework of this project, we want to investigate its extremely promising potential for dermatology and cosmetics industry. Our proposed solution overcomes the fundamental limitations of existing microscopes (confocal / OCT) in terms of penetration depth, resolution and 3D frame rate. It will be a turning point for the early detection of melanoma, which remains a blind spot for current technologies. Beyond this specific problem, its real time capabilities will be exploited for non-invasive angiography in order to identify subsurface vascular and structural features known to be associated with numerous skin diseases. Following the PoC project, we plan to establish a start-up company to further develop the microscope and market it to hospitals and cosmetics industry.
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
- medical and health sciences clinical medicine dermatology
- medical and health sciences clinical medicine oncology skin cancer melanoma
- natural sciences physical sciences optics microscopy confocal microscopy
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Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
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HORIZON.1.1 - European Research Council (ERC)
MAIN PROGRAMME
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Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
HORIZON-ERC-POC - HORIZON ERC Proof of Concept Grants
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Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
(opens in new window) ERC-2023-POC
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Net EU financial contribution. The sum of money that the participant receives, deducted by the EU contribution to its linked third party. It considers the distribution of the EU financial contribution between direct beneficiaries of the project and other types of participants, like third-party participants.
75794 PARIS
France
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.