Project description
Sustainable solubility for the pharmaceutical and chemical industries
Measuring solubility is a necessary but labour-intensive process that often requires substantial amounts of chemicals. Current methods are either fast but inaccurate or slow but precise, both necessitating excessive chemical use. With this in mind, the EIC-funded FASS project offers a sustainable solution to these challenges for the pharmaceutical and chemical industries. It uses high-efficiency second harmonic scattering, combining the analytical advantages of current solubility measurements with fast and accurate performance, cutting-edge sensitivity, and reliability. This solution saves 90 % on costs, reduces measurement time by 90 %, lowers chemical usage by 99 %, cuts electricity consumption by 97 %, and decreases the number of compounds used by 80 % compared to the gold standard.
Objective
Solubility measurement is a standard test that is required for every chemical that is produced or tested. However, measuring solubility is a time/labour-intensive process that requires substantial quantities of chemicals. State-of-the-Art solubility measurements are either fast but inaccurate or slow but accurate and require excess of chemicals. FASS is based on high-efficiency second harmonic scattering that combines the analytical advantages of current solubility measurements, fast and accurate, while achieving cutting edge performance in sensitivity and reliability. FASS saves 90% of cost, 90% of measurement time, 99% of chemicals and 97% of electricity and 80% of compounds compared to the gold standard. As an optical light scattering technique, FASS is non-destructive, and combined with analytical advantages and sustainable use of chemicals and compounds, provides a disruptive innovation in solubility measurement. The consortium is composed of a dedicated startup to bring the instrument to market, a research and technology organization to support technology maturation, a European Research Consortium to enable customer development and instrument demonstration and a center for pharmaceutical research to explore value-added applications of FASS in drug discovery and development. The goals of the project are: 1) to develop a demonstrator with optimized and robust performance suited for instrument demonstration and application exploration. 2) to validate the technology with early adopters in early stage drug discovery and development and chemical synthesis companies. 3) to develop a feasible business model and go-to-market strategy to be implemented by the startup. FASS brings a sustainable solution to the pharmaceutical and chemical industries, reduce chemical and electrical consumption, and through a dedicated startup, will create jobs, foster competition and contribute to the growth of the pharmaceutical industry and the European economy.
Keywords
Programme(s)
- HORIZON.3.1 - The European Innovation Council (EIC) Main Programme
Funding Scheme
HORIZON-EIC - HORIZON EIC GrantsCoordinator
13125 Berlin
Germany