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Revealing the neural computations that distinguish imagination from reality

Project description

How the brain distinguishes reality from imagination

The brain transforms sensory input into a vivid experience of reality and can also generate experiences through imagination. Research indicates that both imagining and perceiving activate similar brain patterns, raising questions about how the brain differentiates between what is real and what is imagined. In this context, the ERC-funded MonitoringReality project aims to test the hypothesis that the brain distinguishes between reality and imagination through a perceptual monitoring process. By using a novel psychophysical paradigm, the project will investigate how sensory processing and cognitive control influence reality judgments and how different signals are integrated to form these judgments. The findings will enhance our understanding of fundamental cognitive processes and provide new insights into reality-monitoring disorders, such as psychosis.

Objective

Our brain is able to turn external signals coming into our senses into a vivid and coherent experience of reality. At the same time, our brain is also able to generate sensory experience in the absence of external signals via imagination. Contrary to our intuition, our experience of reality is not an objective reflection of the external world, since the brain has no direct access to that. Instead, what we perceive as reality is an inference that the brain makes about its own activity, which is both externally driven (by sensory input) and internally driven (by imagination). Recent research has shown that imagining something leads to similar patterns of brain activity as perceiving that same thing in reality. This raises the question; how does the brain determine whether activity represents reality or imagination?

I hypothesize that to distinguish imagination and reality, the brain relies on a perceptual reality monitoring process where higher-order brain regions infer perceptual reality when sensory signals are strong enough and there is low cognitive control. I propose to test this idea by answering three complementary questions: (a) how does sensory processing influence reality judgements? (b) how does cognitive control influence reality judgements? and (c) how are different signals integrated and evaluated to form reality judgements?

To answer these questions, I will use a novel psychophysical paradigm to experimentally induce confusions between imagery and perception in healthy participants. I will precisely characterize neural processes during these confusions by combining state-of-the-art techniques (high-field fMRI, MEG and tRNS), with advanced computational methods (multivariate decoding and Bayesian modelling). The results of this project will increase our fundamental understanding of core cognitive processes such as perception and memory and will provide a novel perspective on disorders of reality monitoring such as psychosis.

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(opens in new window) ERC-2024-STG

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Host institution

UNIVERSITY COLLEGE LONDON
Net EU contribution

Net EU financial contribution. The sum of money that the participant receives, deducted by the EU contribution to its linked third party. It considers the distribution of the EU financial contribution between direct beneficiaries of the project and other types of participants, like third-party participants.

€ 1 477 920,00
Address
GOWER STREET
WC1E 6BT LONDON
United Kingdom

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Region
London Inner London — West Camden and City of London
Activity type
Higher or Secondary Education Establishments
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Total cost

The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.

€ 1 477 920,00

Beneficiaries (1)

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