Numerical modeling of cardiac electrophysiology at the cellular scale

Project Information

MICROCARD-2

Grant agreement ID: 101172576

DOI

10.3030/101172576

EC signature date 7 October 2024

Start date 1 November 2024

End date 30 April 2027

Funded under

• Digital, Industry and Space

Total cost

€ 4 999 300,00

EU contribution

€ 2 499 650,00

Coordinated by

UNIVERSITE DE BORDEAUX
France

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Links to deliverables and publications from FP7 projects, as well as links to some specific result types such as dataset and software, are dynamically retrieved from OpenAIRE .

Publications

Peer reviewed articles (7)

Parallel Algebraic Multigrid Solvers for Composite Discontinuous Galerkin Discretization of the Cardiac EMI Model in Heterogeneous Media

Author(s): Edoardo Centofanti, Ngoc Mai Monica Huynh, Luca F. Pavarino, Simone Scacchi
Published in: Computer Methods in Applied Mechanics and Engineering, Issue 442, 2025, ISSN 0045-7825
Publisher: Elsevier BV
DOI: 10.1016/J.CMA.2025.118001

<i>In silico</i> modelling of multi‐electrode arrays for enhancing cardiac drug testing on hiPSC‐CM heterogeneous tissues

Author(s): Sofia Botti, Rolf Krause, Luca F. Pavarino
Published in: The Journal of Physiology, 2025, ISSN 0022-3751
Publisher: Wiley
DOI: 10.1113/JP287276

Accurate and efficient cardiac digital twin from surface ECGs: Insights into identifiability of ventricular conduction system

Author(s): Thomas Grandits; Karli Gillette; Gernot Plank; Simone Pezzuto
Published in: Medical Image Analysis, 2025, ISSN 1361-8423
Publisher: arXiv
DOI: 10.48550/ARXIV.2411.00165

Correlative imaging integrates electrophysiology with three-dimensional murine heart reconstruction to reveal electrical coupling between cell types

Author(s): Francesco Giardini, Camilla Olianti, Gerard A. Marchal, Fernando Campos, Valentina Romanelli, Joshua Steyer, Josef Madl, Roberto Piersanti, Giulia Arecchi, Induja Perumal Vanaja, Valentina Biasci, Eva A. Rog-Zielinska, Gabriella Nesi, Leslie M. Loew, Elisabetta Cerbai, Stephen P. Chelko, Francesco Regazzoni, Axel Loewe, Martin J. Bishop, Marco Mongillo, Peter Kohl, Tania Zaglia, Callum M. Zgierski-Johnston, Leonardo Sacconi
Published in: Nature Cardiovascular Research, Issue 4, 2025, ISSN 2731-0590
Publisher: Springer Science and Business Media LLC
DOI: 10.1038/S44161-025-00728-9

Computational modelling of biological systems now and then: revisiting tools and visions from the beginning of the century

Author(s): Axel Loewe, Peter J. Hunter, Peter Kohl
Published in: Philosophical Transactions of the Royal Society A: Mathematical, Physical and Engineering Sciences, Issue 383, 2025, ISSN 1364-503X
Publisher: The Royal Society
DOI: 10.1098/RSTA.2023.0384

A BDDC Preconditioner for the Cardiac EMI Model in Three Dimensions

Author(s): Fritz Göbel, Ngoc Mai Monica Huynh, Fatemeh Chegini, Luca Franco Pavarino, Martin Weiser, Simone Scacchi, Hartwig Anzt
Published in: SIAM Journal on Scientific Computing, Issue 48, 2026, ISSN 1064-8275
Publisher: Society for Industrial & Applied Mathematics (SIAM)
DOI: 10.1137/25M1733720

Models of cardiomyocyte–non‐myocyte electrical interactions

Author(s): Ana Simon‐Chica, Axel Loewe, Peter Kohl
Published in: The Journal of Physiology, Issue 604, 2026, ISSN 0022-3751
Publisher: Wiley
DOI: 10.1113/JP287295

Other (1)

Computational Modelling and Simulation of Cardiac Function Now and Then

Author(s): Loewe, Axel
Published in: 2025
Publisher: Zenodo
DOI: 10.5281/ZENODO.17187221