Counter-acting the pandemic potential of flaviviruses: addressing virus-host interactions and defense strategies to design new therapeutics against WNV and DENV

Project Information

InFlaMe

Grant agreement ID: 101191725

DOI

10.3030/101191725

EC signature date 2 December 2024

Start date 1 January 2025

End date 31 December 2028

Funded under

• Health

Total cost

€ 7 995 922,40

EU contribution

€ 7 995 922,40

Coordinated by

FONDAZIONE IRCCS POLICLINICO SAN MATTEO
Italy

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Links to deliverables and publications from FP7 projects, as well as links to some specific result types such as dataset and software, are dynamically retrieved from OpenAIRE .

Publications

Peer reviewed articles (7)

Dissecting the Interaction Domains of SARS-CoV-2 Nucleocapsid Protein and Human RNA Helicase DDX3X and Search for Potential Inhibitors

Author(s): Camilla Lodola, Maria Michela Pallotta, Fabrizio Manetti, Paolo Governa, Emmanuele Crespan, Giovanni Maga, Massimiliano Secchi
Published in: International Journal of Molecular Sciences, Issue 27, 2026, ISSN 1422-0067
Publisher: MDPI AG
DOI: 10.3390/IJMS27020672

Differentiation of West Nile and Usutu Virus Infections by Antibodies Directed to the Non-Structural Protein 1

Author(s): Lena Roßbacher, Samuel Taschler, Elena Cecchettin, Amelie Popovitsch, Stephan W. Aberle, Judith H. Aberle, Iris Medits-Weiss, Karin Stiasny
Published in: Viruses, Issue 17, 2025, ISSN 1999-4915
Publisher: MDPI AG
DOI: 10.3390/V17101357

Increased incidence of human West Nile and Usutu infections in Austria, 2024: analysis of data from 2009 to 2024

Author(s): David M Florian, Jeremy V Camp, Christof Jungbauer, Dirk Werber, Andreas Reich, Karin Stiasny, Stephan W Aberle, Judith H Aberle
Published in: Eurosurveillance, Issue 31, 2026, ISSN 1560-7917
Publisher: European Centre for Disease Control and Prevention (ECDC)
DOI: 10.2807/1560-7917.ES.2026.31.1.2500260

Analysis of West Nile disease convalescents identifies human monoclonal antibodies protective against West Nile and related orthoflaviviruses

Author(s): Tomás Cervantes Rincón, Tereza Frckova, Zaria I. Contejean, Jasmine Cantergiani, Kevin Groen, Benedetta Cena, Simone G. Moro, Filippo Bianchini, Luca Simonelli, David Jarrossay, Silvia Tosolini, Roger Kuratli, Anna R.E. Robinson, Monika Cizkova, Emily G. Niejadlik, Jacques Moritz, Roshan Thakur, Zuzana Krátka, Dragana Mijatović, Jasmina Grujić, Jiri Holoubek, Zorana Budakov-Obradović, Jiri Salat, Václav Hönig, Marija Vraneš, Zvezdana Lojpur, Dajana Lendak, Siniša Sević, Monika Bajči, Lidija Popović-Dragonjić, Biljana Popovska Jovičić, Jagoda Gavrilović, Tania Kapoor, Margaret R. MacDonald, Stylianos Bournazos, Luca Varani, Martin Palus, Benjamin G. Hale, Pavle Banović, Daniel Ruzek, Christopher O. Barnes, Davide F. Robbiani
Published in: Immunity, Issue 59, 2026, ISSN 1074-7613
Publisher: Elsevier BV
DOI: 10.1016/J.IMMUNI.2026.05.013

Single cell RNAseq signatures refined with combiroc enhance identification of NK cells in blood and solid tissues

Author(s): Ivan Ferrari, Saveria Mazzara, Andrea Gobbini, Noemi Di Marzo, Mariacristina Crosti, Sergio Abrignani, Renata Grifantini, Mauro Bombaci, Riccardo L. Rossi
Published in: Scientific Reports, Issue 16, 2026, ISSN 2045-2322
Publisher: Springer Science and Business Media LLC
DOI: 10.1038/S41598-025-29876-5

Type I IFN autoantibodies underlie chikungunya live-attenuated vaccine encephalitis

Author(s): Adrian Gervais, Paul Bastard, Qian Zhang, Marie-Christine Jaffar-Bandjee, Lucy Bizien, Lotfi Dahmane, Marie-Pierre Moiton, Julien Jabot, Radj Cally, Alexis Maillard, Etienne Frumence, Xavier de Lamballerie, Yazdan Yazdanpanah, Jérémie Rosain, Aurélie Cobat, Laurent Abel, Anne Puel, Cyril Ferdynus, Émilie Mosnier, Patrick Gérardin, Shen-Ying Zhang, Jean-Laurent Casanova
Published in: Proceedings of the National Academy of Sciences, Issue 123, 2026, ISSN 0027-8424
Publisher: National Academy of Sciences
DOI: 10.1073/PNAS.2532212123

CIA: unveiling cellular identities with cluster-independent annotation in single-cell RNA sequencing data for comprehensive cell type characterization and exploration

Author(s): Ivan Ferrari, Mattia Battistella, Francesca Vincenti, Andrea Gobbini, Federico Marini, Samuele Notarbartolo, Jole Costanza, Stefano Biffo, Renata Grifantini, Sergio Abrignani, Eugenia Galeota
Published in: BMC Bioinformatics, Issue 27, 2026, ISSN 1471-2105
Publisher: Springer Science and Business Media LLC
DOI: 10.1186/S12859-025-06320-Z