The conserved QTQTX motif in the SARS-CoV-2 spike protein is dispensable for cleavage and lung cell entry of the emerging variant BA.3.2
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Author(s):
Lu Zhang, Nianzhen Chen, Amy Eichmann, Inga Nehlmeier, Ryan Hisner, Christine Happle, Georg M. N. Behrens, Markus Hoffmann, Stefan Pöhlmann
Published in:
Journal of Virology, 2026, ISSN 0022-538X
Publisher:
American Society for Microbiology
DOI:
10.1128/JVI.00691-26
Pseudovirus-based analysis of host cell entry and vaccine-induced neutralisation of Bundibugyo virus
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Author(s):
Markus Hoffmann, Aparna Shandheep, Andreas Pavlou, Katharina Rahmel-Stein, My Linh Ly, Nianzhen Chen, Nicole Moor, Anna-Sophie Moldenhauer, Christian Drosten, Ulrich Kalinke, Marylyn Martina Addo, Stefan Pöhlmann
Published in:
The Lancet Infectious Diseases, Issue 26, 2026, ISSN 1473-3099
Publisher:
Elsevier BV
DOI:
10.1016/S1473-3099(26)00407-X
Lock out: targeting TMPRSS2 to block influenza and coronaviruses
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Author(s):
Lu Zhang, Markus Hoffmann, Stefan Pöhlmann
Published in:
Journal of Virology, Issue 100, 2026, ISSN 0022-538X
Publisher:
American Society for Microbiology
DOI:
10.1128/JVI.00807-25
Design, Synthesis, and Characterization of Dichlorobiphenyl-Derived Inhibitors of the Proprotein Convertase Furin
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Author(s):
Roman W. Lange, Charlotte Boller, Michael Loresch, Konstantin Bloch, Eva Böttcher-Friebertshäuser, Hans Brandstetter, Sven O. Dahms, Torsten Steinmetzer
Published in:
Journal of Medicinal Chemistry, Issue 68, 2025, ISSN 0022-2623
Publisher:
American Chemical Society (ACS)
DOI:
10.1021/ACS.JMEDCHEM.5C02157
