Strengthening epidemiological, genomic and community surveillance of Mpox virus (MPXV) at the Congo River border for DRC and RoC

Informations projet

MPOX-PROBE

N° de convention de subvention: 101195102

DOI

10.3030/101195102

Projet clôturé

Date de signature de la CE 27 Septembre 2024

Date de début 1 Octobre 2024

Date de fin 30 Septembre 2026

Financé au titre de

• Health

Coût total

€ 1 301 868,75

Contribution de l’UE

€ 1 299 993,75

Coordonné par

R-EVOLUTION WORLDWIDE SRL - IMPRESA SOCIALE
Italy

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Livrables

Documents, reports (11)

Midterm recruitment report

 The Midterm recruitment report will include an overview of the number of recruited participants by clinical sites, any problemsin recruitment and, if applicable, a detailed description of implemented and planned measures to compensate for anyincurred delays.

Stewardship plan

To draft Stewardship Plan, outlining how to achieve the optimal use of an intervention, including, for example, how to avoid irrational use, overuse or abuse of health technologies (e.g. antimicrobials)

SOP and video protocol for MPXV detection in sewage complete

A protocol and video demonstrating methodology for collecting wastewater samples and detecting MPXV

Workshop training schedule published

Training schedule for technicians at FCRM and UNIKIN

Project Management Plan (PMP) completed

Includes timelines, deliverables and milestones

Plan for the exploitation and dissemination of results including communication activities

Development of the Exploitation and dissemination plan.

Communication strategy plan prepared

Finalization of communication strategy plan

Description of the MPXV diagnosis method complete

A validated protocol for using the MPXV diagnostic device in humans

Study initiation package

A study initiation package to be elaborated: study preparation for conducting clinical study:•Registration number of the clinical study in a registry complying with the WHO Registry criteria.•Final version of study protocol as approved by the regulator(s) / ethics committee(s)•Regulatory and ethics approvals required for the enrolment of the first study participant

Digital newsletter

Quarterly newsletter with project updates will be released

Developed Research Protocol for Ethic Committee approval

Research Protocol drafted for the applications for Ethics Committee approval.

Websites, patent fillings, videos etc. (1)

Project website

Design, development, implementation, contents management and updating of the project public website

Data Management Plan (2)

Data Management plan

DMP developed and shared with all partners and EDCTP

Updated Data Management plan

DMP revised at M12

Publications

Peer reviewed articles (3)

Assessment of knowledge, perceptions, and preventive practices regarding Mpox among the Congolese population living in Brazzaville

Auteurs: Dého Yvanhe Mbouala Kianguebeni, Ousmane Souare, Claujens Chastel Mfoutou Mapanguy, Jeannhey Christevy Vouvoungui, Oluwatoyosi Olawande, Nafissatou Diallo, Jethro Peya Massala, Marliti Ngambou Nguissaliki, Carine Kades, Olayinka Ilesanmi Stephen, Marcel Tapsou Baïna, Bénie Belle-varide Batanguissa, Youssef Hervé Gnékoumou, Saturnin Nicaise Mokemiabeka, Aristide Gilbert Nianga, Jean Médard Kankou, Alain Maxime Mouanga, Ngashi Ngongo, Mosoka Papa Fallah, Francine Ntoumi
Publié dans: Scientific Reports, 2026, ISSN 2045-2322
Éditeur: Springer Science and Business Media LLC
DOI: 10.1038/S41598-026-64314-0

Mpox outbreaks in Africa constitute a public health emergency of continental security

Auteurs: Nicaise Ndembi, Morenike Oluwatoyin Folayan, Ngashi Ngongo, Francine Ntoumi, Dimie Ogoina, Maha El Rabbat, Jean-Marie Okwo-Bele, Jean Kaseya
Publié dans: The Lancet Global Health, Numéro 12, 2024, ISSN 2214-109X
Éditeur: Elsevier BV
DOI: 10.1016/S2214-109X(24)00363-2

Integrating research into surveillance: enhancing the response to mpox

Auteurs: Francine Ntoumi, Nathalie Strub-Wourgaft
Publié dans: The Lancet, Numéro 405, 2025, ISSN 0140-6736
Éditeur: Elsevier BV
DOI: 10.1016/S0140-6736(25)00247-8