Objective
The fastest-growing food production sector, aquaculture, faces important challenges because of infectious agents. Vaccination is the most effective way to prevent and potentially eradicate such diseases, but to date, most commercial vaccines are administered by injection methods, which for fish, imply many disadvantages. On the other hand, mucosal vaccines (directly administered to mucosal tissues) offer a promising and cost-effective alternative. In my MSCA project, I aspire to bring the field of mucosal immunology to the next level by applying my expertise in immune anatomy and working in the renowned laboratory of Prof. Carolina Tafalla who specializes in characterizing teleost B cells. Through this collaboration, I will uncover the cellular mechanisms and interactions of IgM and IgD B cells at fish mucosal sites, such as gills, skin, and intestines. In these tissues, plasma-like B cells secreting IgM coexist with IgD+IgM- B cells, cells that have lost surface IgM through an unclear recombination event. These cells secrete IgD, suggesting an important but undefined role for IgD at specific mucosal surfaces. At INIA, I will be trained in flow cytometry and single-cell transcriptomics. I will complement these techniques with my knowledge of immune anatomy to comprehensively unveil the role of these mucosal plasma-like cells upon immunization in rainbow trout. This project will innovatively expedite mucosal immunology research and underline my ambitions to become an independent scientist. I will further sharpen my scientist profile through CSIC’s mentoring programs for young researchers, which will enhance my skills in formulating and managing large-scale projects. I will also supervise students, keeping me engaged in the academic sector. The proposal addresses pressing scientific questions by integrating the expertise and network of both the host and me while shaping my path to becoming a senior scientist.
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
- agricultural sciences agriculture, forestry, and fisheries fisheries
- medical and health sciences basic medicine anatomy and morphology
- medical and health sciences basic medicine immunology immunisation
- medical and health sciences basic medicine pharmacology and pharmacy pharmaceutical drugs vaccines
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Keywords
Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)
Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)
Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
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HORIZON.1.2 - Marie Skłodowska-Curie Actions (MSCA)
MAIN PROGRAMME
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Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
HORIZON-TMA-MSCA-PF-EF - HORIZON TMA MSCA Postdoctoral Fellowships - European Fellowships
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Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
(opens in new window) HORIZON-MSCA-2024-PF-01
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Net EU financial contribution. The sum of money that the participant receives, deducted by the EU contribution to its linked third party. It considers the distribution of the EU financial contribution between direct beneficiaries of the project and other types of participants, like third-party participants.
28006 MADRID
Spain
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.