Project description
Better cardiovascular risk prediction in high-risk groups
Heart failure affects millions of people globally, resulting in high healthcare costs and frequent hospitalisations. Current diagnostic tools often fail to predict adverse events. With the support of the Marie Skłodowska-Curie Actions programme, the INSIGHT-LV project will advance prediction by improving the evaluation of left ventricle function in high-risk groups, specifically those with hypertrophic cardiomyopathy (HCM) and COVID-19 patients. HCM lacks updated guidelines and effective predictors, while COVID-19 patients face cardiovascular risks. By using AI, machine learning, and advanced imaging techniques, the project will analyse multimodal data sets to create tools that optimise treatment strategies and personalise decision-making. The results will enhance risk stratification, setting new standards in cardiovascular diagnostics.
Objective
INSIGHT-LV aims to improve cardiovascular risk prediction by enhancing the evaluation of left ventricle function using multimodal methods. Heart failure (HF) affects over 26 million people globally, with high healthcare costs and hospitalization rates. Current diagnostic tools often fail to accurately predict adverse events, highlighting the need for more effective risk prediction models that integrate diverse clinical data.
INSIGHT-LV focuses on two high-risk HF groups: hypertrophic cardiomyopathy (HCM) and COVID-19 patients. HCM, a major cause of sudden cardiac death in young people, lacks updated guidelines and relies on limited predictors. COVID-19 patients show significant cardiovascular risks, creating an urgent need for better risk stratification tools. These two groups represent a substantial part of the HF population requiring improved stratification.
The project will provide clinicians with tools to deliver optimized, cost-effective treatment strategies. By characterizing and stratifying HCM and COVID-19 patients, INSIGHT-LV aims to personalize decision-making and advance disease understanding. Using computational modeling, AI, machine learning, and advanced signal and image processing, the project will integrate multimodal datasets, including ECGs, MRIs, genetic tests, and echocardiography, ensuring robust clinical solutions.
INSIGHT-LV will test AI models on real-world data to validate improvements in predicting risks such as sudden cardiac death and arrhythmias. This work will set new standards for cardiovascular diagnostics, delivering scientific, societal, and economic benefits.
Fields of science (EuroSciVoc)
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CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
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Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)
Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)
Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
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HORIZON.1.2 - Marie Skłodowska-Curie Actions (MSCA)
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Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
HORIZON-TMA-MSCA-PF-EF - HORIZON TMA MSCA Postdoctoral Fellowships - European Fellowships
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Call for proposal
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Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
(opens in new window) HORIZON-MSCA-2024-PF-01
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Net EU financial contribution. The sum of money that the participant receives, deducted by the EU contribution to its linked third party. It considers the distribution of the EU financial contribution between direct beneficiaries of the project and other types of participants, like third-party participants.
20133 Milano
Italy
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.