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Supramolecular Integration of Artificial Molecular Motors in Active Systems : Morphing, Adaptation, Propulsion

Project description

Innovative materials that mimic the energy-driven behaviours of life

Living systems are powered by molecular motors that convert energy into essential functions such as movement, transport, and adaptation. Inspired by this, the ERC-funded SPRING project aims to bring similar active properties to synthetic materials using artificial molecular motors. Unlike current materials that are mostly passive, these motors will drive systems out of equilibrium to enable advanced functions including morphing, self-adaptation, and propulsion. Combining advanced synthetic chemistry and fundamental understanding of molecular systems, SPRING seeks to create innovative (supra)molecular systems, new synthetic objects to study complex matter, and new technologies to apply molecular machines in real-world uses.

Objective

Biomolecular motors are fundamental elements in the emergence of dynamic, self-sustaining, and evolving properties that characterize living systems. When fuelled by an external source of energy, they can perform and convert mechanical work into key functions such as catalysis, regulation, transport, actuation, and locomotion. This transduction of energy happens between hierarchical levels of self-organization, which maintain living systems out of thermodynamic equilibrium and link the unidirectional motion produced by the motors with various emerging functions in a remarkably efficient way. Therefore, one could expect that the implementation of artificial molecular motors in fully synthetic (supra)molecular systems may confer them with some “active” functional properties, in striking contrast with the majority of today’s rather “passive” materials which are engineered and used in (meta)stable states. However, artificial molecular machines have been mainly studied so far as molecular switches, which simply influence their surrounding as a function of their isomerization states (typically A vs B). The objective of the SPRING project is to unambiguously show that the unidirectional motion of artificial molecular motors can be usefully implemented in supramolecular and macromolecular systems and materials, in order to drive them energetically uphill and to subsequently produce non-trivial functions requiring dissipative out-of-equilibrium conditions such as: active morphing, active adaptation, and active propulsion. This will be achieved through advanced synthetic chemistry and a fundamental in-depth understanding of the (supra)molecular and macromolecular systems developed at all scales. If successful, the SPRING project will establish innovative concepts to elaborate (i) active (supra)molecular systems, (ii) new synthetic objects to study some fundamentals of complex matter, and (iii) new technologies to envision applications of molecular machines in the real world.

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Programme(s)

Topic(s)

Funding Scheme

HORIZON-ERC - HORIZON ERC Grants

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Call for proposal

(opens in new window) ERC-2024-ADG

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Host institution

CENTRE INTERNATIONAL DE RECHERCHE AUX FRONTIERES DE LA CHIMIE FONDATION
Net EU contribution
€ 1 148 496,36
Address
ALLEE G MONGE 8
67000 Strasbourg
France
Region
Grand Est Alsace Bas-Rhin
Activity type
Research Organisations
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Total cost
No data

Beneficiaries (3)