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Plastic Degradation by Genetic Engineered Black Soldier Fly using Chitosan Nanocapsules

Project description

Genetically engineered insect larvae for plastic waste management

The use of living organisms to remove or neutralise pollutants from a contaminated site is known as bioremediation and offers an environmentally friendly approach to waste management. This technology is broadly applied in various environmental clean-up efforts, from treating oil spills and contaminated soils to purifying wastewater. With the support of the Marie Skłodowska-Curie Actions programme, the PLASTIFLY project aims to develop a novel bioremediation approach to tackle plastic pollution. Researchers propose to enhance the plastic-degrading potential of the Black Soldier Fly (BSF), which is already used as a bioremediation agent for organic waste. In this context, researchers will employ genetic engineering to introduce plastic-degrading enzymes in BSF larvae.

Objective

The management of plastics, a persistent environmental challenge due to their durability, necessitates innovative solutions. While Black Soldier Fly (BSF) larvae demonstrate potential as a bioremediation agent for organic waste, their capacity for plastic degradation remains limited. This study proposes enhancing the plasticolytic capabilities of BSF larvae through genetic engineering, specifically by introducing plastic-degrading enzymes using CRISPR/Cas9 technology. To overcome the challenges associated with low gene delivery efficiency in insects, we propose employing chitosan-based nanocarriers. These carriers offer biocompatibility, biodegradability, and protection for genetic material. Integrating magnetic nanoparticles into these carriers enables magnetofection, improving gene delivery precision and efficacy. By genetically modifying BSF larvae to degrade plastics, we aim to develop a sustainable, eco-friendly approach to plastic waste management, reducing reliance on harmful chemicals and minimizing environmental impact. This research has the potential to expand beyond conventional plastics, contributing to comprehensive waste management strategies.

Fields of science (EuroSciVoc)

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Keywords

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Programme(s)

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Topic(s)

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Funding Scheme

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HORIZON-TMA-MSCA-PF-EF - HORIZON TMA MSCA Postdoctoral Fellowships - European Fellowships

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Call for proposal

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(opens in new window) HORIZON-MSCA-2024-PF-01

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Coordinator

UNIVERSITA DEGLI STUDI DELL'INSUBRIA
Net EU contribution

Net EU financial contribution. The sum of money that the participant receives, deducted by the EU contribution to its linked third party. It considers the distribution of the EU financial contribution between direct beneficiaries of the project and other types of participants, like third-party participants.

€ 193 643,28
Address
VIA RAVASI 2
21100 VARESE
Italy

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Region
Nord-Ovest Lombardia Varese
Activity type
Higher or Secondary Education Establishments
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Total cost

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