Project description
Peering deeper into the brain
One of science’s biggest problems is understanding how the brain functions, particularly when it comes to observing activity in deep brain regions without harming them. High resolution, minimal invasiveness, and long-term monitoring are difficult to achieve with current imaging techniques. The EIC-funded NEUROGATE project is developing a holographic endoscope that is based on a hair-thin optical fibre. Chronic, high-resolution imaging of neuronal activity in freely moving animal models is made possible by NEUROGATE, which improves essential technologies including bending-resilient fibres and sophisticated brain interfaces. The project's goal is to commercialise this instrument, which will open up new avenues for biomedical research and provide information on how the brain functions in both healthy and diseased conditions.
Objective
Utilising a hair-thin multimode optical fibre, the holographic endoscope allows minimally invasive, high-resolution in-vivo imaging at subcellular levels across any brain structure. The NEUROGATE project will significantly enhance the potential of this breakthrough technology for biomedical imaging by commercialising critical innovations in holographic endoscopy, developed through the prior ERC-PoC projects WOKEGATE and StrokeGATE. The innovations include bending-resilient fibres and brain interfaces, enabling chronic studies, minimising tissue damage and providing flexibility in reconnecting with the region of interest. They make holographic endoscopy the breakthrough technology which enables chronic in-vivo imaging of neuronal signalling and structural connectivity in deep brain regions of freely moving animal models, overcoming several limitations of current technologies. NEUROGATE brings together three academic partners and a commercial venture to validate the system under real-world conditions and achieve TRL6, spinning out the new technology across biomedical research sector, where its potential market exceeds €850 million. This novel tool aims to transform neuroscience by enabling chronic in-vivo monitoring of vitally important brain processes at the microscopic level in both healthy and diseased states, with broad applications in research and medicine.
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
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Keywords
Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)
Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)
Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
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HORIZON.3.1 - The European Innovation Council (EIC)
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Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
HORIZON-EIC - HORIZON EIC Grants
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Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
(opens in new window) HORIZON-EIC-2024-TRANSITION-01
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Net EU financial contribution. The sum of money that the participant receives, deducted by the EU contribution to its linked third party. It considers the distribution of the EU financial contribution between direct beneficiaries of the project and other types of participants, like third-party participants.
07745 Jena
Germany
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.