Objective
Optical coherence tomography (OCT) is a widely adopted non-invasive imaging technique that allows visualizing cross-sectional images of a human eye. Enabling OCT to recover the refractive index (RI) distribution is the holy grail of imaging. It would revolutionize current OCT procedures, offering a quantitative diagnosis for the first time. This, in turn, would open doors to new, unique applications, like highly anticipated next-generation laser vision correction procedures, which today have no quality control tools. Currently, no biomedical imaging method can noninvasively provide live RI distribution of patients’ tissues. This is due to the required reflection mode of measurement. It inherently returns reconstructions with an optical transfer function that covers only the high-frequency region in the spatial-frequency spectrum. To solve this problem, I propose a paradigm shift by changing how we treat OCT signals. Namely, by applying a unique numerical framework, I propose to treat the light returning from the object as if it was transmitted twice through its part. As a result, in my breakthrough idea, OCT becomes a transmission quantitative imaging method in the sense that the measured signal covers a low-frequency region of the spectrum. What is more, my idea is to innovatively combine this novel reformulation with a holographic tomography approach. For this reason, I propose capturing multiple angularly distributed OCT measurements and applying a tailored tomographic reconstruction framework to retrieve the 3D RI distribution of live patients' tissue. This will be the first in the world imaging approach that allows fully quantitative live diagnostic, opening new possibilities not only in medicine (like a live pre- and intraoperative assessment of the tissue) but also in materials engineering (in the high-quality investigation of composite layers) or photonics industry (in the validation of photonic integrated circuits).
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
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Keywords
Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)
Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)
Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
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HORIZON.1.1 - European Research Council (ERC)
MAIN PROGRAMME
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Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
HORIZON-ERC - HORIZON ERC Grants
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Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
(opens in new window) ERC-2025-STG
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Net EU financial contribution. The sum of money that the participant receives, deducted by the EU contribution to its linked third party. It considers the distribution of the EU financial contribution between direct beneficiaries of the project and other types of participants, like third-party participants.
00-661 WARSZAWA
Poland
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.