Project description
Skull fixated stimulation hubs for neurological disorder treatment
Deep brain stimulation (DBS) is a key treatment for neurological diseases for the ageing population. However, there is a need for less invasive alternatives. The BRAINET project consortium has identified spatio-temporal interference stimulation (stIS), a method using pairs of electrodes to precisely target and activate brain rhythms in therapeutic areas without the need for deep brain implantation. With the support of the Marie Skłodowska-Curie Actions programme, BRAINET will develop skull fixated stimulation hubs that create a communication network for therapeutic stimulation. These hubs will use innovative magneto-electrical transducers, powered by external magnetic fields, and advanced electrodes that barely come in contact with the brain. It will also equip researchers with the skills to enhance neurotechnology.
Objective
Invasive Deep Brain Stimulation (DBS) has become an important way to treat neurological diseases within the greying European society making a tether-less improvement desireable.
The BRAINET team is convinced to have identified such an alternative in spatio-temporal Interference Stimulation (stIS). stIS avoids implantation into the brain and uses instead pairs of electrodes to precisely target activating beating rhythms in the depth of the brain at the therapeutic region, without requiring deep seated electrodes. In order to unleash this stimulation power in all regions of the brain, BRAINET sets out to develop skull implantable stimulation hubs which build a communication network and 3D targeting by self-organization, providing semantic information transfer and synchronization, and thus enabling virtual, self-adjusting pairs for therapeutic stIS. These stimulation hubs will be powered by novel magneto-electrical transducer stacks, driven by slowly alternating magnetic fields from the outside and will perform adjustable frequency stimulation by novel nano-modified, compliant electrodes only touching the brain. Network formation will be enabled by multiphysics approaches and ionic in-body communication instantiated in dedicated microelectronic hardware. Preclinical in-vitro and in-vivo testing of devices and methods will allow the community to make important steps towards subsequent clinical implementation of our „Wireless Transcalvarial Brain Stimulators“. BRAINET will allow us to prepare the next generation of researchers, arming them with the knowledge, skills, and visionary insights necessary to drive neuro-technology to replace the present DBS into uncharted, but reliably safer and more flexible territories. BRAINET is an engine for excellence, interdisciplinary convergence, and innovation. Its dual mandate is to establish a training network and thus to lay the groundwork for emerging leaders.
Fields of science (EuroSciVoc)
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CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
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Keywords
Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)
Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)
Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
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HORIZON.1.2 - Marie Skłodowska-Curie Actions (MSCA)
MAIN PROGRAMME
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Topic(s)
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Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
HORIZON-TMA-MSCA-DN - HORIZON TMA MSCA Doctoral Networks
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Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
(opens in new window) HORIZON-MSCA-2024-DN-01
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Net EU financial contribution. The sum of money that the participant receives, deducted by the EU contribution to its linked third party. It considers the distribution of the EU financial contribution between direct beneficiaries of the project and other types of participants, like third-party participants.
79106 Freiburg
Germany
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.