Objective
Cardiac digital twinning is emerging as a cornerstone of precision cardiology, creating patient-specific digital replicas of the heart that integrate anatomy and electromechanical function. These cardiac digital twins (CDTs) promise personalised therapy and improved outcomes. However, current CDT technologies depend on high-quality imaging and electrocardiographic data, limiting their applicability to a small subset of cases.
Cardiorama aims to revolutionise CDTs by enabling anatomical and functional twinning using standard echocardiography (echo) and electrocardiography (ECG). These first-line diagnostic tools are routinely acquired, cost-effective and widely accessible. Echo provides insights into cardiac anatomy and mechanics, while ECG captures the electrical signature of cardiac activation. By leveraging the intrinsic link between electrical activation and mechanical function, combining echo and ECG offers a deeper, synergistic understanding of electromechanical function than either modality alone.
The main challenges of low resolution and spatial sparsity of echo-ECG data will be addressed through generative shape models for anatomy and advanced cardiac modelling for functionalization. Robust uncertainty quantification will provide confidence intervals for model calibration, ensuring reliability and identifying limitations in sparse-data conditions. The developed technology will be applied to two clinical challenges: scar delineation in chronic myocardial infarction and the reconstruction of electrical activation patterns in conduction disorders.
Cardiorama aspires to democratise precision cardiology by creating a fast, affordable, and clinically applicable CDT solution, accessible even in low-resource settings, enabling earlier and more effective treatment of cardiovascular diseases worldwide.
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
- medical and health sciences basic medicine anatomy and morphology
- medical and health sciences clinical medicine cardiology
You need to log in or register to use this function
Keywords
Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)
Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)
Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
-
HORIZON.1.1 - European Research Council (ERC)
MAIN PROGRAMME
See all projects funded under this programme
Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
HORIZON-ERC - HORIZON ERC Grants
See all projects funded under this funding scheme
Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
(opens in new window) ERC-2025-COG
See all projects funded under this callHost institution
Net EU financial contribution. The sum of money that the participant receives, deducted by the EU contribution to its linked third party. It considers the distribution of the EU financial contribution between direct beneficiaries of the project and other types of participants, like third-party participants.
38122 TRENTO
Italy
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.