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Transitioning Psychotropic Alkaloids From Plants And Mushrooms To Neuroprotective Agents: Incorporating Computational Tools For The Development Of Novel Therapeutics

Objective

The NeuroHEALTH project aims to address the growing challenge of neurodegenerative diseases, such as Alzheimer's and Parkinson's, which affect millions worldwide and impose significant social and economic burdens. The project will harness the potential of neglected natural products (NPs), like alkaloids, from psychotropic plants and mushrooms that till recently had regulatory constrains. The integration of state of the art phytochemical analysis, with advanced computational tools will accelerate the discovery of novel NPs. In vitro and in vivo testing assays including zebrafish models will evaluate the safety and efficacy to reveal compounds of interest, that can enhance cognitive health and improve quality of life. Bioactive extracts and NPs will be scaled up and formulated in combination with a market analysis, sustainability and intellectual properties assessment will ensure that findings are relevant and applicable.

Through strategic secondments and staff exchanges among academic and industry partners, NeuroHEALTH will foster interdisciplinary collaboration, enhancing knowledge transfer and innovation. Workshops, conferences, and outreach activities will engage diverse stakeholders, including professionals, policymakers, and the general public, promoting awareness of the project's findings and their implications for health care. By bridging the gap between traditional knowledge and modern science, NeuroHEALTH aims to deliver impactful solutions for neurodegenerative diseases, ultimately contributing to healthier aging populations. This timely initiative not only addresses urgent societal needs but also positions Europe at the forefront of innovative research in natural product-based therapeutics.

Fields of science (EuroSciVoc)

CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.

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Keywords

Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)

Programme(s)

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Topic(s)

Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.

Funding Scheme

Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.

HORIZON-TMA-MSCA-SE - HORIZON TMA MSCA Staff Exchanges

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Call for proposal

Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.

(opens in new window) HORIZON-MSCA-2024-SE-01

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Coordinator

ETHNIKO KAI KAPODISTRIAKO PANEPISTIMIO ATHINON
Net EU contribution

Net EU financial contribution. The sum of money that the participant receives, deducted by the EU contribution to its linked third party. It considers the distribution of the EU financial contribution between direct beneficiaries of the project and other types of participants, like third-party participants.

€ 320 640,00
Address
6 CHRISTOU LADA STR
105 61 ATHINA
Greece

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Region
Αττική Aττική Κεντρικός Τομέας Αθηνών
Activity type
Higher or Secondary Education Establishments
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Total cost

The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.

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Participants (9)

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