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CORDIS

DUO 4 ALL

Project description

A minimally invasive device for heart valve disorders

Tricuspid regurgitation (TR) is a heart valve disorder in which the tricuspid valve fails to close properly, allowing blood to flow backward into the right atrium. Although highly prevalent and linked to mortality and hospitalisations, TR remains underdiagnosed. The EIC-funded DUO 4 ALL project aims to address the limited treatment options available for TR by developing a minimally invasive system. The generated device adapts to the valve closing problem of each patient while preserving the anatomy of the heart. Importantly, it is easy to implant and is expected to improve the clinical outcome and quality of life of millions of patients worldwide.

Objective

CroíValve is developing DUO 4 All, a Best-In-Class minimally invasive solution for severe Tricuspid Regurgitation (TR). It is a clear unmet clinical need, with significant impact on mortality, cardiovascular events and quality of life of the large population suffering with this disease.
With the highest prevalence of all heart valve diseases, TR is a significant clinical and commercial opportunity.
It poses unique challenges in comparison with other heart valve diseases and so needs a solution specifically designed to overcome
these challenges.
The CroíValve DUO 4 All Tricuspid Coaptation Valve System is a novel approach that provides the right solution for the right heart.
The approach puts both the patient and physician at the centre of the design by ensuring it is safe, effective, can accommodate the range of patient anatomies and is quick to learn and implant.

Fields of science (EuroSciVoc)

Keywords

Programme(s)

Topic(s)

Funding Scheme

HORIZON-EIC-ACC - HORIZON EIC Accelerator

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Call for proposal

(opens in new window) HORIZON-EIC-2025-ACCELERATOR-02

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Coordinator

CROIVALVE LIMITED
Net EU contribution
€ 2 493 375,00
Address
UNIT A GF, THE LIFFEY TRUST CENTRE, 117-125 UPPER SHERIFF STREET
D01 Y0E7 Dublin
Ireland
SME
Yes
Region
Ireland Eastern and Midland Dublin
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Links
Total cost
No data