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HYdrogel-based Matrices for Advanced Tissue Engineering

Objective

Tissue decellularization is a well-established technique in tissue engineering to preserve the biochemical complexity of native tissues. However, its application in recreating the tumor stroma for in vitro studies remains limited, with current models often relying on non-specific extracellular matrices that lack the unique characteristics of the tumor microenvironment. Here, we present a novel technology to develop hydrogels from decellularized tumor tissue using a tumor cell culture-derived matrix. This new technology, developed as part of the ERC project ICoMICS, improves the preservation of the composition of the matrix, in contrast to currently available alternatives. Hence, this technology creates a market opportunity to improve the development of hydrogels not only for cancer modeling, but also for a wide range of potential applications in disease modeling and regenerative medicine. In addition, by leveraging our extensive expertise in hydrogel characterization, we will expand our products not only for the production of specific hydrogels, but also for the characterization of all types of hydrogels according to the specific needs of potential users.
Therefore, the main objective of this proof of concept is to assess the potential of this project to evolve into a spin-off company focused on:
1) commercializing novel hydrogels for tumor and disease modeling, and
2) providing potential customers with a wide range of accessible and thorough characterization methods.
In addition, we aim to assess the market opportunities for both the commercialization of our hydrogel products and the establishment of a specialized characterization service providing in-depth physicochemical analysis of biomaterials for research groups and industry stakeholders.

Fields of science (EuroSciVoc)

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Programme(s)

Multi-annual funding programmes that define the EU’s priorities for research and innovation.

Topic(s)

Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.

Funding Scheme

Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.

HORIZON-ERC-POC - HORIZON ERC Proof of Concept Grants

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Call for proposal

Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.

(opens in new window) ERC-2025-POC

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Host institution

UNIVERSIDAD DE ZARAGOZA
Net EU contribution

Net EU financial contribution. The sum of money that the participant receives, deducted by the EU contribution to its linked third party. It considers the distribution of the EU financial contribution between direct beneficiaries of the project and other types of participants, like third-party participants.

€ 150 000,00
Address
CALLE PEDRO CERBUNA 12
50009 ZARAGOZA
Spain

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Region
Noreste Aragón Zaragoza
Activity type
Higher or Secondary Education Establishments
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Total cost

The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.

No data

Beneficiaries (1)

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